| Literature DB >> 28985045 |
Wei Lin1,2, Yong-Xiang Zheng1, Zhan Xun1, Zhi-Bin Huang1, Da-Qing Shi1.
Abstract
A microwave-assisted regioselective synthesis of 3-functionalized indole derivatives via a three-component domino reaction of anilines, arylglyoxal monohydrates, and cyclic 1,3-dicarbonyl compounds is described. The main advantages of this protocol are short reaction times, practical simplicity, its metal-free nature, the availability of starting materials, green solvents, and high regioselectivity.Entities:
Keywords: indole; microwave-assisted; three-component reaction
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Year: 2017 PMID： 28985045 DOI： 10.1021/acscombsci.7b00126
Source DB: PubMed Journal: ACS Comb Sci ISSN： 2156-8944 Impact factor: 3.784