| Literature DB >> 28982643 |
Orianna DeMasi1,2, Sidney Feygin3, Aluma Dembo4, Adrian Aguilera5,6, Benjamin Recht1.
Abstract
BACKGROUND: Automatically tracking mental well-being could facilitate personalization of treatments for mood disorders such as depression and bipolar disorder. Smartphones present a novel and ubiquitous opportunity to track individuals' behavior and may be useful for inferring and automatically monitoring mental well-being.Entities:
Keywords: depression; mobile health; smartphones
Year: 2017 PMID: 28982643 PMCID: PMC5649042 DOI: 10.2196/mhealth.7820
Source DB: PubMed Journal: JMIR Mhealth Uhealth ISSN: 2291-5222 Impact factor: 4.773
Daily measures of activity and sleep and how they were calculated.
| Type of measure | Measure | How it was measured and calculated |
| Time | Day of study (semester) | Coded as the number of days since the first day of the study. |
| Day of week | Ordinal variable coded Monday (0) through Sunday (6). | |
| Sleep | Sleep duration | Longest contiguous time that the participant was not physically active starting after 9 PM. |
| Activity | Daytime activity | Fraction of time a participant was physically active during the median active period. The median active period is the time between the median hour the participant became physically active during each day of the study and the median hour that the participant stopped being active during the study. |
| Nighttime stillness | Fraction of time the phone was predicted to be still, that is, set down, during the median still period. The median still period was calculated over the course of the study to be the median hour that the longest contiguous still period started and the median hour it stopped. |
Participant baseline characteristics. Averages across individuals are reported with standard deviations in parenthesis, except where indicated. Where appropriate, numbers represent the average across individuals of averages within individuals.
| Participant measure | Included participants | Included participants | Excluded participants |
| Agea | 19.83 (1.99) | 20.33 (1.60) | 20.80 (4.13) |
| Female (number)a | 26 | 3 | 28 |
| BDI-20b score (entry)a | 11.14 (9.27) | 7.33 (3.54) | 12.61 (7.20) |
| BDI-20b score (exit)a | 11.98 (12.00) | N/A | N/A |
| Median mood rating | 5.17 (1.63) | 5.83 (0.90) | 5.44 (1.44) |
| Median energy rating | 5.60 (1.27) | 6.67 (0.94) | 5.98 (0.80) |
| Number of emotion surveys completed | 160.51 (44.42) | 139.33 (55.01) | 30.25 (50.97) |
| Number of days with emotion ratings | 49.45 (8.27) | 44.00 (11.06) | 10.49 (15.99) |
| Reported typical sleep duration in hours (from exit survey)a | 6.88 (1.35) | N/A | N/A |
| Average duration of inactive period in hours (sensed | 8.79 (1.22) | 8.56 (0.48) | N/A |
| Number of times per month a participant exercised (from exit survey)a | 4.24 (5.04) | N/A | N/A |
| Average minutes active per day (sensed | 118.78 (32.67) | 151.25 (59.68) | N/A |
| Number of days with sensed activity and mood input | 38.60 (9.15) | 40.00 (9.64) | 3.36 (5.15) |
aIndicates measures averaged only over submitted responses, as entry and exit survey questions were optional.
bBDI-20 indicates optional self-reports to 20 questions of the Beck’s Depression Inventory (the question related to suicidal ideation was omitted).
Results of fixed-effects for linear mixed-effects model of mood level from smartphone-measured and time variables. The measure for nighttime stillness was excluded from the otherwise maximal random-effects structure.
| Fixed-effect | Estimate | Standard error | ||
| Mean mood (intercept) | 5.056 | 0.174 | 28.973 (49.0) | <.001 |
| Day of study (semester) | −0.059 | 0.261 | −0.226 (47.0) | .82 |
| Day of week (coded 0-6, Monday-Sunday) | 0.040 | 0.076 | 0.528 (257.0) | .60 |
| Sleep duration | 0.072 | 0.030 | 2.451 (52.0) | .02 |
| Daytime activity | 0.097 | 0.032 | 3.062 (50.4) | .004 |
| Nighttime stillness | 0.040 | 0.026 | 1.528 (1881.5) | .13 |
Checking model fits for linear mixed-effects model of mood.
| Model name | Akaike information | Bayesian information | Log likelihood | Chi-square value | |
| Random intercept only | 6522.0 | 6538.8 | −3258.0 | ||
| Fixed-effects with random intercept only | 6508.8 | 6553.7 | −3246.4 | 23.2 (5) | <.001 |
| Maximal random-effects structure | 6322.0 | 6445.4 | −3139.0 | 214.8 (14) | <.001 |
Fixed-effects for a mixed-effects linear model relating daily energy level from smartphone-measured and time variables. The ordinal variable for weekday was excluded from the near-maximal random-effects structure.
| Fixed-effect | Estimate | Standard error | ||
| Mean energy (intercept) | 5.686 | 0.184 | 30.857 (53.9) | <.001 |
| Day of study (semester) | −0.304 | 0.233 | −1.303 (49.4) | .20 |
| Day of week (coded 0-6, Monday-Sunday) | 0.196 | 0.067 | 2.912 (1876.2) | .004 |
| Sleep duration | −0.027 | 0.031 | −0.858 (57.7) | .39 |
| Daytime activity | 0.182 | 0.039 | 4.673 (49.6) | <.001 |
| Nighttime stillness | 0.024 | 0.030 | 0.810 (50.4) | .42 |
Checking model fits for linear mixed-effects model of energy.
| Model name | Akaike information | Bayesian information | Log likelihood | Chi-square value | |
| Random intercept only | 6284.2 | 6301.0 | −3139.1 | ||
| Fixed-effects with random intercept only | 6196.1 | 6240.9 | −3090.0 | 98.1 (5) | <.001 |
| Maximal random-effects structure | 5972.5 | 6095.9 | −2964.2 | 251.6 (14) | <.001 |
Statistics on linear models predicting daily well-being from activity measures. Whereas the models provide an improvement overall, there is a range in the ability to model individuals. The P values are for permutation tests, checking whether user lift is greater than 0, that is, whether models are significantly more accurate than always predicting each individual to be at their most frequent state.
| Problem (model) | Well-being measure | Average | Minimum | Maximum | |
| Good or bad day (penalized logistic regression) | Mood (Prediction error) | 5.44% | −21.74% | 35.00% | .001 |
| Energy (Prediction error) | 4.92% | −22.73% | 39.39% | .008 | |
| Daily average (linear regression with elastic net) | Mood (RMSEa) | 0.026 | −0.232 | 0.48 | .08 |
| Energy (RMSE) | 0.048 | −0.169 | 0.575 | .01 |
aRMSE: root-mean-square error.