Literature DB >> 28982336

Multi-Target Metal-Based Anticancer Agents.

Zhen-Feng Chen1, Chris Orvig2, Hong Liang1.   

Abstract

There has been a growing interest in the rational design of multi-targeted drugs with the aim of enhancing overall efficacy and/or improving safety. The development of multi-targeted drugs might yield new avenues in the treatment of cancers that involve multiple pathogenic factors. In this review, we focus on the multi-targeted metal-based anticancer agents, which include platinum, ruthenium, rhodium, gold, silver, copper, cobalt, zinc, and nickel complexes. Future directions for the development of multi-targeted metal-based anticancer agents are also proposed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Multi-target; anticancer agents; cytotoxicity; metal complexes; nickel complexes; pathogenic factors.

Mesh：

Substances：

Year:  2017        PMID： 28982336     DOI： 10.2174/1568026617666171004155437

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  6 in total

Review 1.  Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition.

Authors:  Karim Zuhra; Fiona Augsburger; Tomas Majtan; Csaba Szabo
Journal:  Biomolecules       Date:  2020-04-30

2.  Spectroscopy, Structure, Biomacromolecular Interactions, and Antiproliferation Activity of a Fe(II) Complex With DPA-Bpy as Pentadentate Ligand.

Authors:  Hehe Bai; Jia Shi; Qingyu Guo; Wenming Wang; Zhigang Zhang; Yafeng Li; Manohar Vennampalli; Xuan Zhao; Hongfei Wang
Journal:  Front Chem       Date:  2022-04-25       Impact factor: 5.545

Review 3.  Bioactivity and Development of Small Non-Platinum Metal-Based Chemotherapeutics.

Authors:  Maria Grazia Ferraro; Marialuisa Piccolo; Gabriella Misso; Rita Santamaria; Carlo Irace
Journal:  Pharmaceutics       Date:  2022-04-28       Impact factor: 6.525

4.  Evaluation of anticancer activity in vitro of a stable copper(I) complex with phosphine-peptide conjugate.

Authors:  Urszula K Komarnicka; Barbara Pucelik; Daria Wojtala; Monika K Lesiów; Grażyna Stochel; Agnieszka Kyzioł
Journal:  Sci Rep       Date:  2021-12-14       Impact factor: 4.379

5.  Copper-Containing Nanoparticles and Organic Complexes: Metal Reduction Triggers Rapid Cell Death via Oxidative Burst.

Authors:  Sergey A Tsymbal; Anna A Moiseeva; Nikol A Agadzhanian; Svetlana S Efimova; Alina A Markova; Dmitry A Guk; Olga O Krasnovskaya; Victoria M Alpatova; Andrei V Zaitsev; Anna V Shibaeva; Victor V Tatarskiy; Marina S Dukhinova; Valentina A Ol'shevskaya; Olga S Ostroumova; Elena K Beloglazkina; Alexander A Shtil
Journal:  Int J Mol Sci       Date:  2021-10-14       Impact factor: 5.923

6.  Induction of Redox-Mediated Cell Death in ER-Positive and ER-Negative Breast Cancer Cells by a Copper(II)-Phenolate Complex: An In Vitro and In Silico Study.

Authors:  Vaiyapuri Subbarayan Periasamy; Anvarbatcha Riyasdeen; Venugopal Rajendiran; Mallayan Palaniandavar; Hanumanthappa Krishnamurthy; Ali Abdullah Alshatwi; Mohammad Abdulkader Akbarsha
Journal:  Molecules       Date:  2020-10-01       Impact factor: 4.411
  6 in total

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