Literature DB >> 28980139

Evidence of depression-associated circadian rhythm disruption and regret in prostate cancer patients after surgery.

Joanne Christie1, Christopher F Sharpley2, Vicki Bitsika3, David Christie4,5.   

Abstract

PURPOSE: The purpose of this study is to investigate the association between prostate cancer (PCa) patients' regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood, anhedonia) and a symptom of melancholic depression (disruption to circadian rhythm).
METHODS: Forty PCa patients who had received surgery for their PCa completed a postal survey including background information, regret about surgery that 'did them a lot of harm' and three items drawn from the Zung Self-Rating Depression Scale measuring depressed mood, anhedonia and circadian rhythm disruption.
RESULTS: There were significant correlations between all three symptoms of depression (depressed mood, anhedonia, disruption to circadian rhythm) and between patients' regret that surgery did them a lot of harm and their circadian rhythm disruption, but not between depressed mood or anhedonia and regret about surgery doing harm.
CONCLUSIONS: These findings suggest that PCa patients' post-surgery regrets about major harm may lead to a significant disruption in a central physiological function and raise the need to consider this side effect of surgery when planning supportive services for these men.

Entities:  

Keywords:  Circadian rhythm; Melancholia; Prostate cancer; Regrets; Surgery

Mesh:

Year:  2017        PMID: 28980139     DOI: 10.1007/s00520-017-3913-3

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  7 in total

1.  A SELF-RATING DEPRESSION SCALE.

Authors:  W W ZUNG
Journal:  Arch Gen Psychiatry       Date:  1965-01

2.  The heterogeneity of the depressive syndrome: when numbers get serious.

Authors:  S D Ostergaard; S O W Jensen; P Bech
Journal:  Acta Psychiatr Scand       Date:  2011-08-13       Impact factor: 6.392

3.  Long-term decision regret after post-prostatectomy image-guided intensity-modulated radiotherapy.

Authors:  Thomas P Shakespeare; Stephen Chin; Lucy Manuel; Shelly Wen; Matthew Hoffman; Shea W Wilcox; Noel J Aherne
Journal:  J Med Imaging Radiat Oncol       Date:  2016-08-16       Impact factor: 1.735

Review 4.  Circadian rhythm disturbances in depression.

Authors:  Anne Germain; David J Kupfer
Journal:  Hum Psychopharmacol       Date:  2008-10       Impact factor: 1.672

5.  Validation of a decision regret scale.

Authors:  Jamie C Brehaut; Annette M O'Connor; Timothy J Wood; Thomas F Hack; Laura Siminoff; Elisa Gordon; Deb Feldman-Stewart
Journal:  Med Decis Making       Date:  2003 Jul-Aug       Impact factor: 2.583

6.  The role of Melancholia in prostate cancer patients' depression.

Authors:  Christopher F Sharpley; Vicki Bitsika; David R Christie
Journal:  BMC Psychiatry       Date:  2011-12-20       Impact factor: 3.630

Review 7.  The chronobiology and neurobiology of winter seasonal affective disorder.

Authors:  Robert D Levitan
Journal:  Dialogues Clin Neurosci       Date:  2007       Impact factor: 5.986

  7 in total

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