Literature DB >> 28980110

Facile, eco-friendly, catalyst-free synthesis of polyfunctionalized quinoxalines.

Yaohong Zhang1, Mengqiang Luo1, Yan Li1, Hai Wang2, Xiaorong Ren1, Chenze Qi3.   

Abstract

A novel, facile and eco-friendly synthesis of quinoxalines from [Formula: see text] and 1,2-diamines was developed. An attractive feature of this protocol is that the desired products could be generated efficiently in water and without any catalyst, which is in accordance with the aim of green chemistry. A plausible mechanism has been proposed.

Entities:  

Keywords:  1, 2-Diamines; Catalyst-free; Eco-friendly; Quinoxalines; Water

Mesh：

Substances：

Year:  2017        PMID： 28980110     DOI： 10.1007/s11030-017-9777-0

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  17 in total

1.  Laterally-extended porphyrin systems incorporating a switchable unit.

Authors:  Maxwell J Crossley; Lesley A Johnston
Journal:  Chem Commun (Camb)       Date:  2002-05-21       Impact factor: 6.222

2.  Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).

Authors:  George R Pettit; Fiona Hogan; Jun-Ping Xu; Rui Tan; Toshihiko Nogawa; Zbigniew Cichacz; Robin K Pettit; Jiang Du; Qing-Hua Ye; Gordon M Cragg; Cherry L Herald; Michael S Hoard; Animesh Goswami; Justin Searcy; Larry Tackett; Dennis L Doubek; Lee Williams; John N A Hooper; Jean M Schmidt; Jean-Charles Chapuis; Denise N Tackett; Felicia Craciunescu
Journal:  J Nat Prod       Date:  2008-03-08       Impact factor: 4.050

3.  A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ.

Authors:  Dulce Maroni; Sandeep Rana; Chandrani Mukhopadhyay; Amarnath Natarajan; Mayumi Naramura
Journal:  Immunol Lett       Date:  2015-10-27       Impact factor: 3.685

4.  Pharmacokinetic-pharmacodynamic modeling of the effect of varenicline on nicotine craving in adult smokers.

Authors:  Patanjali Ravva; Marc R Gastonguay; Hélène M Faessel; Theodore C Lee; Raymond Niaura
Journal:  Nicotine Tob Res       Date:  2014-08-21       Impact factor: 4.244

5.  Visible-light-induced, copper(I)-catalysed C-N coupling between o-phenylenediamine and terminal alkynes: one-pot synthesis of 3-phenyl-2-hydroxy-quinoxalines.

Authors:  Arunachalam Sagadevan; Ayyakkannu Ragupathi; Kuo Chu Hwang
Journal:  Photochem Photobiol Sci       Date:  2013-12       Impact factor: 3.982

6.  Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor.

Authors:  Laetitia J Martin; Andreas L Marzinzik; Steven V Ley; Ian R Baxendale
Journal:  Org Lett       Date:  2010-12-16       Impact factor: 6.005

7.  Synthesis of Quinoxaline Derivatives via Tandem Oxidative Azidation/Cyclization Reaction of N-Arylenamines.

Authors:  Haichao Ma; Dianjun Li; Wei Yu
Journal:  Org Lett       Date:  2016-02-10       Impact factor: 6.005

8.  Structure-activity studies of echinomycin antibiotics against drug-resistant and biofilm-forming Staphylococcus aureus and Enterococcus faecalis.

Authors:  Aaron M Socha; Kerry L Laplante; David J Russell; David C Rowley
Journal:  Bioorg Med Chem Lett       Date:  2009-01-10       Impact factor: 2.823

9.  Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways.

Authors:  Qiong Wei; Haijuan Liu; Honghao Zhou; Dejun Zhang; Zhiwei Zhang; Qibing Zhou
Journal:  BMC Cancer       Date:  2015-03-21       Impact factor: 4.430

10.  A new small molecule inhibitor of soluble guanylate cyclase.

Authors:  Filipa Mota; Paul Gane; Kathryn Hampden-Smith; Charles K Allerston; John Garthwaite; David L Selwood
Journal:  Bioorg Med Chem       Date:  2015-08-04       Impact factor: 3.641
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