Literature DB >> 28979501

Hyperventilation-related hyperlactataemia in a case of paroxysmal vocal cord dysfunction.

Mohamed M Mohamed1, Jon Sturman1.   

Abstract

Paroxysmal Vocal Cords Dysfunction(PVCD), also known as paradoxical vocal cord motion, is abnormal adduction of the vocal cords during inspiration. Like asthma, PCVD can be triggered by breathing in lung irritants, upper respiratory infection or exercise. However, unlike asthma, PCVD is not an immune system reaction and does not involve the lower airways. Treatment for the two conditions differs. Plasma lactate levels are usually associated with acidosis and an increased risk of poor outcome and are described in a number of disease states of circulatory and/or respiratory failure. In patients with psychogenic hyperventilation, high lactates are associated with hypocapnia and alkalosis and should not necessarily be considered as an adverse sign. We describe a case of a young patient with PCVD mimicking asthma with high plasma lactate and discuss the mechanisms involved.

Entities:  

Keywords:  Paroxymal vocal cords dysfunction; lactate

Year:  2016        PMID: 28979501      PMCID: PMC5606519          DOI: 10.1177/1751143716638369

Source DB:  PubMed          Journal:  J Intensive Care Soc        ISSN: 1751-1437


  8 in total

Review 1.  Vocal cord dysfunction in bronchial asthma. A review article.

Authors:  Majdy Idrees; J Mark FitzGerald
Journal:  J Asthma       Date:  2014-11-20       Impact factor: 2.515

2.  Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation.

Authors:  W E HUCKABEE
Journal:  J Clin Invest       Date:  1958-02       Impact factor: 14.808

Review 3.  pH control of lactic acid and keto acid production: a mechanism of acid-base regulation.

Authors:  V L Hood; R L Tannen
Journal:  Miner Electrolyte Metab       Date:  1983

4.  On the mechanism of hypophosphatemia during acute hyperventilation: evidence for increased muscle glycolysis.

Authors:  N Brautbar; H Leibovici; S G Massry
Journal:  Miner Electrolyte Metab       Date:  1983 Jan-Feb

5.  Elevated lactate during psychogenic hyperventilation.

Authors:  E ter Avest; F M Patist; J C Ter Maaten; M W N Nijsten
Journal:  Emerg Med J       Date:  2010-07-20       Impact factor: 2.740

6.  Cyclic AMP suppresses the inhibition of glycolysis by alternative oxidizable substrates in the heart.

Authors:  C Depre; S Ponchaut; J Deprez; L Maisin; L Hue
Journal:  J Clin Invest       Date:  1998-01-15       Impact factor: 14.808

7.  Paradoxical Vocal-Cord Dysfunction: Management in Athletes.

Authors:  Katherine R Newsham; Bernice K Klaben; Victor J Miller; Jan E Saunders
Journal:  J Athl Train       Date:  2002-09       Impact factor: 2.860

8.  Vocal cord dysfunction: a frequently forgotten entity.

Authors:  S Campainha; C Ribeiro; M Guimarães; R Lima
Journal:  Case Rep Pulmonol       Date:  2012-09-16
  8 in total

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