Literature DB >> 28978773

Lipid and Carbohydrate Metabolism in Caenorhabditis elegans.

Jennifer L Watts1, Michael Ristow2.   

Abstract

Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, C. elegans synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in C. elegans We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
Copyright © 2017 by the Genetics Society of America.

Entities:  

Keywords:  Caenorhabditis elegans; WormBook; ascarosides; cholesterol; fatty acids; glucose; maradolipids; phospholipids; sphingolipids; triacylglycerols

Mesh:

Year:  2017        PMID: 28978773      PMCID: PMC5629314          DOI: 10.1534/genetics.117.300106

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  333 in total

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  63 in total

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