| Literature DB >> 28978598 |
Meltiady Issa1, Ioannis Milioglou2.
Abstract
The cancer immunotherapy field has had many promising developments in recent years. Checkpoint inhibitors are good examples of that. This new class of medications comes with a new constellation of side effects that require early recognition and management. Here we present a patient with metastatic adenocarcinoma on pembrolizumab who was admitted to the hospital for colitis. This was found to be an immune-related adverse event from pembrolizumab. We discuss our work-up and approach to the diagnosis, then highlight important treatment pearls for internal medicine physicians who are increasingly taking care of such patients. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Entities:
Keywords: immunological products and vaccines; malignant disease and immunosuppression; unwanted effects / adverse reactions
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Year: 2017 PMID: 28978598 PMCID: PMC5652473 DOI: 10.1136/bcr-2017-221319
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X