Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cancer biology: Genome jail-break triggers lockdown.

Literature DB >> 28976957

Cancer biology: Genome jail-break triggers lockdown.

Neil T Umbreit¹, David Pellman¹.

Abstract

Entities: Disease

Mesh：
Biology
Humans
Neoplasms

Year: 2017 PMID： 28976957 DOI： 10.1038/nature24146

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

× No keyword cloud information.

18 in total

1. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.

Authors: Juan Fu; David B Kanne; Meredith Leong; Laura Hix Glickman; Sarah M McWhirter; Edward Lemmens; Ken Mechette; Justin J Leong; Peter Lauer; Weiqun Liu; Kelsey E Sivick; Qi Zeng; Kevin C Soares; Lei Zheng; Daniel A Portnoy; Joshua J Woodward; Drew M Pardoll; Thomas W Dubensky; Young Kim
Journal: Sci Transl Med Date: 2015-04-15 Impact factor: 17.956

2. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.

Authors: Adam Freund; Christopher K Patil; Judith Campisi
Journal: EMBO J Date: 2011-03-11 Impact factor: 11.598

Review 3. Aging, cellular senescence, and cancer.

Authors: Judith Campisi
Journal: Annu Rev Physiol Date: 2012-11-08 Impact factor: 19.318

4. Programmed cell senescence during mammalian embryonic development.

Authors: Daniel Muñoz-Espín; Marta Cañamero; Antonio Maraver; Gonzalo Gómez-López; Julio Contreras; Silvia Murillo-Cuesta; Alfonso Rodríguez-Baeza; Isabel Varela-Nieto; Jesús Ruberte; Manuel Collado; Manuel Serrano
Journal: Cell Date: 2013-11-14 Impact factor: 41.582

5. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.

Authors: Xiao-Dong Li; Jiaxi Wu; Daxing Gao; Hua Wang; Lijun Sun; Zhijian J Chen
Journal: Science Date: 2013-08-29 Impact factor: 47.728

6. Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

Authors: Selene Glück; Baptiste Guey; Muhammet Fatih Gulen; Katharina Wolter; Tae-Won Kang; Niklas Arndt Schmacke; Anne Bridgeman; Jan Rehwinkel; Lars Zender; Andrea Ablasser
Journal: Nat Cell Biol Date: 2017-07-31 Impact factor: 28.824

7. cGAS surveillance of micronuclei links genome instability to innate immunity.

Authors: Karen J Mackenzie; Paula Carroll; Carol-Anne Martin; Olga Murina; Adeline Fluteau; Daniel J Simpson; Nelly Olova; Hannah Sutcliffe; Jacqueline K Rainger; Andrea Leitch; Ruby T Osborn; Ann P Wheeler; Marcin Nowotny; Nick Gilbert; Tamir Chandra; Martin A M Reijns; Andrew P Jackson
Journal: Nature Date: 2017-07-24 Impact factor: 49.962

8. p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation.

Authors: Yunfei Chen; Lufan Wang; Jiali Jin; Yi Luan; Cong Chen; Yu Li; Hongshang Chu; Xinbo Wang; Guanghong Liao; Yue Yu; Hongqi Teng; Yanming Wang; Weijuan Pan; Lan Fang; Lujian Liao; Zhengfan Jiang; Xin Ge; Bin Li; Ping Wang
Journal: J Exp Med Date: 2017-03-02 Impact factor: 14.307

9. Mitotic progression following DNA damage enables pattern recognition within micronuclei.

Authors: Shane M Harding; Joseph L Benci; Jerome Irianto; Dennis E Discher; Andy J Minn; Roger A Greenberg
Journal: Nature Date: 2017-07-31 Impact factor: 49.962

10. Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Authors: Zhixun Dou; Kanad Ghosh; Maria Grazia Vizioli; Jiajun Zhu; Payel Sen; Kirk J Wangensteen; Johayra Simithy; Yemin Lan; Yanping Lin; Zhuo Zhou; Brian C Capell; Caiyue Xu; Mingang Xu; Julia E Kieckhaefer; Tianying Jiang; Michal Shoshkes-Carmel; K M Ahasan Al Tanim; Glen N Barber; John T Seykora; Sarah E Millar; Klaus H Kaestner; Benjamin A Garcia; Peter D Adams; Shelley L Berger
Journal: Nature Date: 2017-10-04 Impact factor: 49.962

6 in total

Cancer biology: Genome jail-break triggers lockdown.

1. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.

2. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.

Review 3. Aging, cellular senescence, and cancer.

4. Programmed cell senescence during mammalian embryonic development.

5. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.

6. Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

7. cGAS surveillance of micronuclei links genome instability to innate immunity.

8. p38 inhibition provides anti-DNA virus immunity by regulation of USP21 phosphorylation and STING activation.

9. Mitotic progression following DNA damage enables pattern recognition within micronuclei.

10. Cytoplasmic chromatin triggers inflammation in senescence and cancer.

1. Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase.

2. Oxidative stress induces senescence and sterile inflammation in murine amniotic cavity.

3. Nuclear envelope assembly defects link mitotic errors to chromothripsis.

Review 4. Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype.

Review 5. Lipid and protein dynamics that shape nuclear envelope identity.

6. Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway.