Literature DB >> 28976637

Applications of Microfluidics in Quantitative Biology.

Yang Bai1, Meng Gao1, Lingling Wen1, Caiyun He1, Yuan Chen1, Chenli Liu1, Xiongfei Fu1, Shuqiang Huang1.   

Abstract

Quantitative biology is dedicated to taking advantage of quantitative reasoning and advanced engineering technologies to make biology more predictable. Microfluidics, as an emerging technique, provides new approaches to precisely control fluidic conditions on small scales and collect data in high-throughput and quantitative manners. In this review, the authors present the relevant applications of microfluidics to quantitative biology based on two major categories (channel-based microfluidics and droplet-based microfluidics), and their typical features. We also envision some other microfluidic techniques that may not be employed in quantitative biology right now, but have great potential in the near future.
© 2017 Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences. Biotechnology Journal Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Keywords:  lab-on-chip; micro/nanofluidics; quantitative biology; synthetic biology; systems biology

Mesh:

Year:  2017        PMID: 28976637     DOI: 10.1002/biot.201700170

Source DB:  PubMed          Journal:  Biotechnol J        ISSN: 1860-6768            Impact factor:   4.677


  6 in total

Review 1.  Microfluidics for Peptidomics, Proteomics, and Cell Analysis.

Authors:  Rui Vitorino; Sofia Guedes; João Pinto da Costa; Václav Kašička
Journal:  Nanomaterials (Basel)       Date:  2021-04-26       Impact factor: 5.076

Review 2.  Microfluidics for Biotechnology: Bridging Gaps to Foster Microfluidic Applications.

Authors:  Vera Ortseifen; Martina Viefhues; Lutz Wobbe; Alexander Grünberger
Journal:  Front Bioeng Biotechnol       Date:  2020-11-13

3.  Facile microfabrication of three dimensional-patterned micromixers using additive manufacturing technology.

Authors:  Doheon Koo; Hongyun So
Journal:  Sci Rep       Date:  2022-04-15       Impact factor: 4.996

4.  A portable and affordable aligner for the assembly of microfluidic devices.

Authors:  Victoria Guglielmotti; Nicolás Andrés Saffioti; Ana Laura Tohmé; Martín Gambarotta; Gastón Corthey; Diego Pallarola
Journal:  HardwareX       Date:  2022-08-27

5.  Emergence of qualitative states in synthetic circuits driven by ultrasensitive growth feedback.

Authors:  Juan Ramon Melendez-Alvarez; Xiao-Jun Tian
Journal:  PLoS Comput Biol       Date:  2022-09-16       Impact factor: 4.779

6.  Toward uncharted territory of cellular heterogeneity: advances and applications of single-cell RNA-seq.

Authors:  Brandon Lieberman; Meena Kusi; Chia-Nung Hung; Chih-Wei Chou; Ning He; Yen-Yi Ho; Josephine A Taverna; Tim H M Huang; Chun-Liang Chen
Journal:  J Transl Genet Genom       Date:  2021-01-01
  6 in total

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