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Literature DB >> 2897632

Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila.

K Blochlinger¹, R Bodmer, J Jack, L Y Jan, Y N Jan.

Abstract

In the absence of cut gene activity in Drosophila, external sensory organs are transformed into chordotonal organs. Here we show that the cut locus encodes a large protein containing a homoeodomain and is expressed in nuclei of cells in external sensory organs but not in cells within chordotonal organs.

Entities: Gene Species

Mesh：

Year: 1988 PMID： 2897632 DOI： 10.1038/333629a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

76 in total

1. The locus-controlling region (LCR) from the cut locus of Drosophila activates the reporter gene lacZ periodically.

Authors: N E Ivanov; N A Tchurikov
Journal: Dokl Biochem Biophys Date: 2001 May-Jun Impact factor: 0.788

2. In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein.

Authors: Jude Canon; Utpal Banerjee
Journal: Genes Dev Date: 2003-04-01 Impact factor: 11.361

3. C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).

Authors: A Khanna-Gupta; T Zibello; H Sun; J Lekstrom-Himes; N Berliner
Journal: Proc Natl Acad Sci U S A Date: 2001-07-03 Impact factor: 11.205

4. Detection of DNA domains in Drosophila, human, and plant chromosomes possessing mainly 50- to 150-kilobase stretches of DNA.

Authors: N A Tchurikov; N A Ponomarenko
Journal: Proc Natl Acad Sci U S A Date: 1992-08-01 Impact factor: 11.205

10. The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.

Authors: F Mailly; G Bérubé; R Harada; P L Mao; S Phillips; A Nepveu
Journal: Mol Cell Biol Date: 1996-10 Impact factor: 4.272

Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila.

1. The locus-controlling region (LCR) from the cut locus of Drosophila activates the reporter gene lacZ periodically.

2. In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein.

3. C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).

4. Detection of DNA domains in Drosophila, human, and plant chromosomes possessing mainly 50- to 150-kilobase stretches of DNA.

5. Methods and algorithms for statistical analysis of protein sequences.

6. Four distinct regulatory regions of the cut locus and their effect on cell type specification in Drosophila.

7. Control of the spineless antennal enhancer: direct repression of antennal target genes by Antennapedia.

8. Evidence that the homeodomain protein Gtx is involved in the regulation of oligodendrocyte myelination.

Review 9. Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases.

10. The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.