| Literature DB >> 28973416 |
Philip Coish1, Bryan W Brooks2,3, Evan P Gallagher4, Margaret Mills4, Terrance J Kavanagh4, Nancy Simcox4, Grace A Lasker4, Dianne Botta4, Stephanie C Schmuck4, Adelina Voutchkova-Kostal5, Jakub Kostal5, Melissa L Mullins3, Suzanne M Nesmith6, Karolina E Mellor1, Jone Corrales2,3, Lauren A Kristofco2,3, Gavin N Saari2,3, Baylor Steele2,3, Longzhu Q Shen1, Fjodor Melnikov1, Julie B Zimmerman1,7, Paul T Anastas1,7.
Abstract
Herein, we provide an overview of a research network that is aimed at fostering interdisciplinary collaboration between chemists and toxicologists with the goal of rationally designing safer commercial chemicals. The collaborative is the Molecular Design Research Network (MoDRN) that was created in 2013 with funding from the EPA-National Science Foundation Networks for Sustainable Molecular Design and Synthesis (NSMDS) program. MoDRN is led by 4 universities, Baylor University, University of Washington, The George Washington University, and Yale University. The overarching goal of the network is to enable and empower the design of safer chemicals based on the fourth Principle of Green Chemistry that states, "chemical products should be designed to preserve efficacy of function while minimizing toxicity."Entities:
Keywords: computational methods; green chemistry; guidelines; in silico models; molecular design; molecular properties; nexus; safer chemical design; systems thinking; toxicology
Mesh:
Year: 2018 PMID: 28973416 DOI: 10.1093/toxsci/kfx175
Source DB: PubMed Journal: Toxicol Sci ISSN: 1096-0929 Impact factor: 4.849