Literature DB >> 28969274

Comparison of the Effect of Fluoride Varnish, Chlorhexidine Varnish and Casein Phosphopeptide- Amorphous Calcium Phosphate (CPP-ACP) Varnish on Salivary Streptococcus mutans Level: A Six Month Clinical Study.

Punit Manish Patel1, Shivayogi M Hugar2, Seema Halikerimath3, Chandrashekhar M Badakar4, Niraj S Gokhale4, Prachi J Thakkar1, Divyata Kohli1, Shreyas Shah1.   

Abstract

INTRODUCTION: Dental caries is the most widespread disease which has a multi factorial origin. Streptococcus mutans is considered to be the chief pathogen in its development. Different varnishes are available which can be used for the prevention of the carious process. AIM: To compare the effect of fluoride varnish, chlorhexidine varnish and fluoride varnish containing Casein Phosphopeptide - Amorphous Calcium Phosphate (CPP-ACP) on salivary Streptococcusmutans count in children with mixed dentition over a period of six months.
MATERIALS AND METHODS: Seventy two children of age 6-12 years with mixed dentition were selected fulfilling inclusion and exclusion criteria and divided into three groups: Group I- Fluoride varnish group; Group II- Chlorhexidine varnish group; Group III- MI varnish (fluoride varnish containing CPP-ACP) group. After thorough oral prophylaxis and restorative treatment the varnishes were applied to the teeth once a week for four consecutive weeks in the respective groups. Salivary Streptococcus mutans count (CFU/ml of saliva) was estimated at baseline, 1 month, 3 months and 6 months after varnish application. Bonferroni post-hoc test and paired t-test for inter group and intra group comparison was used in the study.
RESULTS: A statistically significant reduction in salivary S. mutans colony count was seen with all three groups at all the different time intervals. Maximum reduction was noted in chlorhexidine varnish group at all the intervals after varnish application.
CONCLUSION: Prevention of dental caries plays a vital role in paediatric dental practice. The use of dental varnish has proved to be effective in reducing the dental caries. Chlorhexidine varnish was found to show maximum reduction in salivary S. mutans count for six month period, when compared to MI varnish and fluoride varnish. Thus, chlorhexidine varnish can be used as potent caries inhibiting agent and promote good oral health.

Entities:  

Keywords:  Children; Demineralization; Dental caries; Prevention; Remineralization; Saliva

Year:  2017        PMID: 28969274      PMCID: PMC5620921          DOI: 10.7860/JCDR/2017/26541.10409

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  28 in total

1.  In situ effect of frequent sucrose exposure on enamel demineralization and on plaque composition after APF application and F dentifrice use.

Authors:  A F Paes Leme; R Dalcico; C P M Tabchoury; A A Del Bel Cury; P L Rosalen; J A Cury
Journal:  J Dent Res       Date:  2004-01       Impact factor: 6.116

2.  Minimum intervention dentistry principles and objectives.

Authors:  L J Walsh; A M Brostek
Journal:  Aust Dent J       Date:  2013-06       Impact factor: 2.291

3.  Effect of different chlorhexidine varnish regimens on mutans streptococci levels in interdental plaque and saliva.

Authors:  S Twetman; L G Petersson
Journal:  Caries Res       Date:  1997       Impact factor: 4.056

Review 4.  Chlorhexidine varnishes: a review.

Authors:  S Matthijs; P A Adriaens
Journal:  J Clin Periodontol       Date:  2002-01       Impact factor: 8.728

Review 5.  Dental caries. An infectious and transmissible disease.

Authors:  P W Caufield; A L Griffen
Journal:  Pediatr Clin North Am       Date:  2000-10       Impact factor: 3.278

6.  Correlation of level and duration of Streptococcus mutans infection with incidence of dental caries.

Authors:  I Zickert; C G Emilson; B Krasse
Journal:  Infect Immun       Date:  1983-02       Impact factor: 3.441

7.  The effect of chlorhexidine varnish treatment on salivary mutans streptococcal levels in child orthodontic patients.

Authors:  H J Sandham; L Nadeau; H I Phillips
Journal:  J Dent Res       Date:  1992-01       Impact factor: 6.116

Review 8.  Professional topical fluoride applications--clinical efficacy and mechanism of action.

Authors:  B Ogard; L Seppä; G Rølla
Journal:  Adv Dent Res       Date:  1994-07

9.  Factors Affecting the Formation, Severity and Location of White Spot Lesions during Orthodontic Treatment with Fixed Appliances.

Authors:  Khaled Khalaf
Journal:  J Oral Maxillofac Res       Date:  2014-04-01

10.  An in vitro evaluation of the demineralization inhibitory effect of F(-) varnish and casein phosphopeptide-amorphous calcium phosphate on enamel in young permanent teeth.

Authors:  Vinola Duraisamy; Ananda Xavier; Ullal Anand Nayak; Venugopal Reddy; Arun Prasad Rao
Journal:  J Pharm Bioallied Sci       Date:  2015-08
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  7 in total

1.  Antimicrobial effectiveness of Nano Silver Fluoride Varnish in reducing Streptococcus mutans in saliva and plaque biofilm when compared with Chlorhexidine and Sodium Fluoride Varnishes.

Authors:  Nandita Waikhom; Nidhi Agarwal; Zohra Jabin; Ashish Anand
Journal:  J Clin Exp Dent       Date:  2022-04-01

2.  Prevalence of Caries According to the ICDAS II in Children from 6 and 12 Years of Age from Southern Ecuadorian Regions.

Authors:  Eleonor Vélez-León; Alberto Albaladejo; Katherine Cuenca-León; Magaly Jiménez-Romero; Ana Armas-Vega; María Melo
Journal:  Int J Environ Res Public Health       Date:  2022-06-14       Impact factor: 4.614

3.  Comparative Evaluation of the Remineralizing Efficacy of Fluoride Varnish and its Combination Varnishes on White Spot Lesions in Children with ECC: A Randomized Clinical Trial.

Authors:  Sarangapani Radha; Gurusamy Kayalvizhi; Sanguida Adimoulame; Gajula S Prathima; Kirthika Muthusamy; G Ezhumalai; Nagendrababu Jagadesaan
Journal:  Int J Clin Pediatr Dent       Date:  2020 Jul-Aug

4.  Caries Activity and Ph Level Changes after Fluoride Varnish and Casein Phosphopeptides-Amorphous Calcium Phosphate Application on Children's Saliva.

Authors:  Anie Apriani; Armelia Sari Widyarman; E Arlia Budiyanti; Boedi Oetomo Roeslan
Journal:  Contemp Clin Dent       Date:  2020-08-07

5.  In vitro Comparison of Antimicrobial Activity of Conventional Fluoride Varnishes Containing Xylitol and Casein Phosphopeptide-Amorphous Calcium Phosphate.

Authors:  Karim Jafari; Somayeh Hekmatfar; Maryam Fereydunzadeh
Journal:  J Int Soc Prev Community Dent       Date:  2018-07-18

6.  Comparative Evaluation of Different Varnishes and Pit and Fissure Sealants on Streptococcus mutans Count in Saliva of Children.

Authors:  Rachna Sharma; Natasha Ghambir; Nidhi Gupta; Rashi Singh
Journal:  Int J Clin Pediatr Dent       Date:  2022 May-Jun

Review 7.  Application of Selected Biomaterials and Stem Cells in the Regeneration of Hard Dental Tissue in Paediatric Dentistry-Based on the Current Literature.

Authors:  Alina Wrzyszcz-Kowalczyk; Maciej Dobrzynski; Iwona Grzesiak-Gasek; Wojciech Zakrzewski; Monika Mysiak-Debska; Patrycja Nowak; Malgorzata Zimolag; Rafal J Wiglusz
Journal:  Nanomaterials (Basel)       Date:  2021-12-13       Impact factor: 5.076

  7 in total

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