Literature DB >> 28969184

A Rare Case of Pulmonary Lymphangitic Carcinomatosis in a Young Adult with Carcinoma Stomach.

Prasanta Kumar Bhattacharya1, Md Jamil2, Yookarin Khonglah3, Aakash Roy4, Murti V Subrahmanya4.   

Abstract

Pulmonary Lymphangitic Carcinomatosis (PLC) occurs in about 6-8% of patients with lung metastasis and may rarely develop in the course of gastric cancer representing a complication due to diffuse metastasis in the lymphatics of the lungs. A 29-year-old female, admitted with difficulty in breathing and productive cough for one week, was initially evaluated for respiratory tract infection. During evaluation of associated anaemia an upper gastrointestinal endoscopy showed large ulcerative growth in the lesser curvature of the stomach suggestive of carcinoma. A High Resolution Computed Tomographic (HRCT) scan of the lungs was done for evaluation of the pulmonary opacities on chest x-ray which showed nodular thickening of interlobular septa with peribronchial cuffing and fissural thickening. The biopsy of the gastric ulcer was suggestive of poorly differentiated malignancy. With the cumulative results of the investigations a diagnosis of poorly differentiated carcinoma of stomach with pulmonary metastasis as lymphangitic carcinomatosis was made. PLC is an extremely rare manifestation of metastatic gastric cancer. Though associated with an extremely poor prognosis, advanced gastric cancer in younger patients presenting with symptoms and signs of respiratory disease should alert the physician of a possible diagnosis of PLC.

Entities:  

Keywords:  Gastric cancer; Lung manifestation; Young female

Year:  2017        PMID: 28969184      PMCID: PMC5620825          DOI: 10.7860/JCDR/2017/27352.10397

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

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Journal:  Indian J Surg Oncol       Date:  2011-03-05

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Journal:  Eur J Radiol       Date:  2009-04-28       Impact factor: 3.528

3.  Gastric cancer: two epidemics?

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Journal:  Dig Dis Sci       Date:  2011-05       Impact factor: 3.199

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Authors:  Kong Zhang; Yong Huang
Journal:  Ai Zheng       Date:  2006-09

5.  Global cancer statistics.

Authors:  Ahmedin Jemal; Freddie Bray; Melissa M Center; Jacques Ferlay; Elizabeth Ward; David Forman
Journal:  CA Cancer J Clin       Date:  2011-02-04       Impact factor: 508.702

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Authors:  D M Bruce; S D Heys; O Eremin
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Review 7.  Pulmonary lymphangitic carcinomatosis as a primary manifestation of gastric carcinoma in a young adult: a case report and review of the literature.

Authors:  Kim Moubax; Wim Wuyts; Vincent Vandecaveye; Hans Prenen
Journal:  BMC Res Notes       Date:  2012-11-16

Review 8.  Pulmonary lymphangitic carcinomatosis in liver carcinoma: a rare case report and literature review.

Authors:  Li Zhuang; Xiangyan Liu; Chen Hu; Lin Zhang; Guoping Jiang; Jian Wu; Shusen Zheng
Journal:  World J Surg Oncol       Date:  2014-03-27       Impact factor: 2.754

  8 in total

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