Literature DB >> 28967388

Epidemiologic study of 230 cases of testicular/paratesticular tumors or masses: 15-year experience of a single center.

Jian Shen1, Yunli Bi2, Xiang Wang1, Liangsheng Lu1, Liangfeng Tang1, Ying Liu1, Hong Chen1, Bin Zhang1.   

Abstract

PURPOSE: This study retrospectively investigated the cases of testicular tumors/masses treated in our center from 2002 to 2017 and analyzed their epidemiologic features.
METHODS: Data were collected by searching our center's database using "testicular tumor" or "testicular mass" as keywords. Patients not operated in our hospital were excluded. Preoperative serum alpha-fetoprotein (AFP) levels were reviewed in germ cell tumor (GCT) cases and analyzed to predict malignancy in various age groups.
RESULTS: In total, 230 cases were identified: 151 were benign (78 in the left, 72 in the right, and 1 bilateral) with 3.63years mean age during the operation, and 79 were malignant (42 in the left, 36 in the right, and 1 bilateral) with 2.21years mean age during the operation. Main pathological diagnoses were mature teratoma (92, 40.00%), yolk sac tumor (53, 23.04%), dermoid cyst (23, 10.00%), embryonic carcinoma (15, 6.53%), immature teratoma (14, 6.09%), benign cyst (8, 3.48%), Leydig cell tumor (6, 2.61%), and paratesticular rhabdomyosarcoma (5, 2.17%). All GCT cases with AFP >1000ng/ml, >100ng/ml, >20ng/ml were malignant in <7-, 7-9-, and ≥10-month-old groups, respectively.
CONCLUSIONS: Radical inguinal orchiectomy without biopsy is suggested in 7-9- and ≥10-month-old cases with AFP >100ng/ml and >20ng/ml, respectively. TYPE OF STUDY: Retrospective Study. LEVEL OF EVIDENCE: Level III-IV.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AFP; Children; Germ cell tumor; Testicular tumor

Mesh:

Year:  2017        PMID: 28967388     DOI: 10.1016/j.jpedsurg.2017.08.027

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  1 in total

1.  Paratesticular Dermoid Cyst Mimicking a Torsed Supernumerary Testis: A Case Report.

Authors:  Manuel Betancourt-Torres; Laura Figueroa-Diaz; Wilma Rodriguez-Mojica
Journal:  Am J Case Rep       Date:  2020-10-18
  1 in total

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