Literature DB >> 28966908

The link between ADHD-like inattention and obsessions and compulsions during treatment of youth with OCD.

Andrew G Guzick1,2, Joseph P H McNamara1, Adam M Reid3, Amanda M Balkhi1,2, Eric A Storch4,5,6,7,8, Tanya K Murphy4,5,6, Wayne K Goodman9, Regina Bussing1,2, Gary R Geffken10.   

Abstract

Attention-deficit/hyperactivity disorder (ADHD) has been found to be highly comorbid in children and adolescents with obsessive-compulsive disorder (OCD). Some have proposed, however, that obsessive anxiety may cause inattention and executive dysfunction, leading to inappropriate ADHD diagnoses in those with OCD. If this were the case, these symptoms would be expected to decrease following successful OCD treatment. The present study tested this hypothesis and evaluated whether ADHD symptoms at baseline predicted OCD treatment response. Obsessive-compulsive and ADHD symptoms were assessed in 50 youth enrolled in a randomized controlled trial investigating selective serotonin reuptake inhibitor and cognitive behavioral treatment. Repeated-measures analysis of variance (RMANOVA) revealed that ADHD symptoms at baseline do not significantly predict treatment outcome. A multivariate RMANOVA found that OCD treatment response moderated change in inattention; participants who showed greater reduction in OCD severity experienced greater reduction in ADHD-inattentive symptoms, while those with less substantial reduction in obsessions and compulsions showed less change. These findings suggest that children and adolescents with OCD and inattention may experience meaningful improvements in attention problems following OCD treatment. Thus, in many youth with OCD, inattention may be inherently tied to obsessions and compulsions. Clinicians may consider addressing OCD in treatment before targeting inattentive-type ADHD.

Entities:  

Year:  2016        PMID: 28966908      PMCID: PMC5619255          DOI: 10.1016/j.jocrd.2016.11.004

Source DB:  PubMed          Journal:  J Obsessive Compuls Relat Disord        ISSN: 2211-3649            Impact factor:   1.677


  35 in total

1.  Familiality of Tourette syndrome, obsessive-compulsive disorder, and attention-deficit/hyperactivity disorder: heritability analysis in a large sib-pair sample.

Authors:  Carol A Mathews; Marco A Grados
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2010-11-18       Impact factor: 8.829

2.  Comorbidity of obsessive-compulsive disorder and attention-deficit/hyperactivity disorder in referred children and adolescents.

Authors:  Gabriele Masi; Stefania Millepiedi; Maria Mucci; Nicoletta Bertini; Chiara Pfanner; Francesca Arcangeli
Journal:  Compr Psychiatry       Date:  2006 Jan-Feb       Impact factor: 3.735

3.  Understanding the covariation of tics, attention-deficit/hyperactivity, and obsessive-compulsive symptoms: A population-based adult twin study.

Authors:  Rebecca Pinto; Benedetta Monzani; James F Leckman; Christian Rück; Eva Serlachius; Paul Lichtenstein; David Mataix-Cols
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2016-02-27       Impact factor: 3.568

4.  The impact of depression on the treatment of obsessive-compulsive disorder: results from a 5-year follow-up.

Authors:  Gideon E Anholt; Idan M Aderka; Anton J L M van Balkom; Johannes H Smit; Haggai Hermesh; Els de Haan; Patricia van Oppen
Journal:  J Affect Disord       Date:  2011-09-01       Impact factor: 4.839

5.  Methylphenidate-induced obsessive-compulsiveness.

Authors:  S Kouris
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1998-02       Impact factor: 8.829

6.  Dysregulation in pediatric obsessive compulsive disorder.

Authors:  Joseph F McGuire; Brent J Small; Adam B Lewin; Tanya K Murphy; Alessandro S De Nadai; Vicky Phares; Gary Geffken; Eric A Storch
Journal:  Psychiatry Res       Date:  2013-04-25       Impact factor: 3.222

7.  Comparative neuropsychology of adult obsessive-compulsive disorder and attention deficit/hyperactivity disorder: implications for a novel executive overload model of OCD.

Authors:  Amitai Abramovitch; Reuven Dar; Haggai Hermesh; Avraham Schweiger
Journal:  J Neuropsychol       Date:  2011-12-02       Impact factor: 2.864

8.  Psychometric evaluation of the Children's Yale-Brown Obsessive-Compulsive Scale.

Authors:  Eric A Storch; Tanya K Murphy; Gary R Geffken; Ohel Soto; Muhammad Sajid; Pam Allen; Jonathan W Roberti; Erin M Killiany; Wayne K Goodman
Journal:  Psychiatry Res       Date:  2004-11-30       Impact factor: 3.222

9.  Impact of comorbidity on cognitive-behavioral therapy response in pediatric obsessive-compulsive disorder.

Authors:  Eric A Storch; Lisa J Merlo; Michael J Larson; Gary R Geffken; Heather D Lehmkuhl; Marni L Jacob; Tanya K Murphy; Wayne K Goodman
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2008-05       Impact factor: 8.829

10.  Behavioral Impulsivity in Obsessive-Compulsive Disorder.

Authors:  Amitai Abramovitch; Dean McKay
Journal:  J Behav Addict       Date:  2016-05-09       Impact factor: 6.756

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  2 in total

Review 1.  Diagnostic Issues in Early-Onset Obsessive-Compulsive Disorder and their Treatment Implications.

Authors:  Elisabetta Burchi; Stefano Pallanti
Journal:  Curr Neuropharmacol       Date:  2019       Impact factor: 7.363

Review 2.  Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management.

Authors:  Ahsan Nazeer; Finza Latif; Aisha Mondal; Muhammad Waqar Azeem; Donald E Greydanus
Journal:  Transl Pediatr       Date:  2020-02
  2 in total

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