| Literature DB >> 28966404 |
Kristen M McGraw1, Greggory T Kent1, Joseph R Gonzalez1, Ihsan Erden1, Weiming Wu1.
Abstract
The interaction of various 1,2-dibromides with NEt3 under various conditions (THF and DMF, respectively) at different temperatures was investigated. Our results from these reactions show that substrate dependent dehydrobrominations compete with reductive debrominations. A comprehensive discussion of these competitive pathways is offered.Entities:
Keywords: Basicity; Debromination; Dehydrobromination; E1cB; α-CH acidity
Year: 2017 PMID： 28966404 PMCID： PMC5619868 DOI： 10.1016/j.tetlet.2017.04.024
Source DB: PubMed Journal: Tetrahedron Lett ISSN： 0040-4039 Impact factor: 2.415