Literature DB >> 28965871

FOXO1: Another avenue for treating digestive malignancy?

Feiyu Shi1, Tian Li2, Zhi Liu3, Kai Qu4, Chengxin Shi1, Yaguang Li1, Qian Qin1, Liang Cheng1, Xin Jin1, Tianyu Yu1, Wencheng Di5, Jianwen Que6, Hongping Xia7, Junjun She8.   

Abstract

Digestive malignancies are the leading cause of mortality among all neoplasms, contributing to estimated 3 million deaths in 2012 worldwide. The mortality rate hassurpassed lung cancer and prostate cancer in recent years. The transcription factor Forkhead Box O1 (FOXO1) is a key member of Forkhead Box family, regulating diverse cellular functions during tumor initiation, progression and metastasis. In this review, we focus on recent studies investigating the antineoplastic role of FOXO1 in digestive malignancy. This review aims to serve as a guide for further research and implicate FOXO1 as a potent therapeutic target in digestive malignancy.
Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Akt; Digestive malignancy; Forkhead box O1; Hepatocellular carcinoma; microRNA

Mesh：

Substances：

Year:  2017        PMID： 28965871      PMCID： PMC5874167          DOI： 10.1016/j.semcancer.2017.09.009

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN： 1044-579X            Impact factor:   15.707


  109 in total

1.  Olfactory learning deficits in mutants for leonardo, a Drosophila gene encoding a 14-3-3 protein.

Authors:  E M Skoulakis; R L Davis
Journal:  Neuron       Date:  1996-11       Impact factor: 17.173

Review 2.  eIF2α phosphorylation as a biomarker of immunogenic cell death.

Authors:  Oliver Kepp; Michaela Semeraro; José Manuel Bravo-San Pedro; Norma Bloy; Aitziber Buqué; Xing Huang; Heng Zhou; Laura Senovilla; Guido Kroemer; Lorenzo Galluzzi
Journal:  Semin Cancer Biol       Date:  2015-03-06       Impact factor: 15.707

Review 3.  Models of carcinogenesis: an overview.

Authors:  Paolo Vineis; Arthur Schatzkin; John D Potter
Journal:  Carcinogenesis       Date:  2010-04-29       Impact factor: 4.944

4.  Estrogen receptor β: switching to a new partner and escaping from estrogen.

Authors:  Yuet-Kin Leung; Shuk-Mei Ho
Journal:  Sci Signal       Date:  2011-04-12       Impact factor: 8.192

5.  The oncoprotein HBXIP suppresses gluconeogenesis through modulating PCK1 to enhance the growth of hepatoma cells.

Authors:  Hui Shi; Runping Fang; Yinghui Li; Leilei Li; Weiying Zhang; Huawei Wang; Fuquan Chen; Shuqin Zhang; Xiaodong Zhang; Lihong Ye
Journal:  Cancer Lett       Date:  2016-09-05       Impact factor: 8.679

6.  Interplay of miR-21 and FoxO1 modulates growth of pancreatic ductal adenocarcinoma.

Authors:  Weifeng Song; Lei Wang; Liwei Wang; Qi Li
Journal:  Tumour Biol       Date:  2015-01-27

Review 7.  Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.

Authors:  Jinho Heo; Rebeka Eki; Tarek Abbas
Journal:  Semin Cancer Biol       Date:  2015-09-30       Impact factor: 15.707

8.  Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer.

Authors:  Ji Hun Kim; Min Kyu Kim; Hee Eun Lee; Sung Jin Cho; Yu Jin Cho; Byung Lan Lee; Hye Seung Lee; Seon Young Nam; Jae-Seon Lee; Woo Ho Kim
Journal:  Mod Pathol       Date:  2007-05-11       Impact factor: 7.842

9.  From cirrhosis to hepatocellular carcinoma in HCV-infected patients: genes involved in tumor progression.

Authors:  Y Wang; J Li; J Chen; L Liu; Z Peng; J Ding; K Ding
Journal:  Eur Rev Med Pharmacol Sci       Date:  2012-08       Impact factor: 3.507

10.  Forkhead Transcription Factor FOXO1 Inhibits Angiogenesis in Gastric Cancer in Relation to SIRT1.

Authors:  Sue Youn Kim; Young San Ko; Jinju Park; Yiseul Choi; Jong-Wan Park; Younghoon Kim; Jung-Soo Pyo; Young Bok Yoo; Jae-Seon Lee; Byung Lan Lee
Journal:  Cancer Res Treat       Date:  2015-03-03       Impact factor: 4.679
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  15 in total

1.  MiR-28-5p promotes human glioblastoma cell growth through inactivation of FOXO1.

Authors:  Guohua Zhu; Zengliang Wang; Maimaitili Mijiti; Guojia Du; Yandong Li; Geng Dangmurenjiafu
Journal:  Int J Clin Exp Pathol       Date:  2019-08-01

2.  Timeless-Stimulated miR-5188-FOXO1/β-Catenin-c-Jun Feedback Loop Promotes Stemness via Ubiquitination of β-Catenin in Breast Cancer.

Authors:  Yujiao Zou; Xian Lin; Junguo Bu; Zelong Lin; Yanjuan Chen; Yunhui Qiu; Haiyue Mo; Yao Tang; Weiyi Fang; Ziqing Wu
Journal:  Mol Ther       Date:  2019-09-03       Impact factor: 11.454

3.  Combination of Geriatric Nutritional Risk Index and Carcinoembryonic Antigen to Predict the Survival of Patients With Colorectal Cancer.

Authors:  Hailun Xie; Lishuang Wei; Guanghui Yuan; Mingxiang Liu; Yanren Liang; Shunhui Gao; Qiwen Wang; Xin Lin; Shuangyi Tang; Jialiang Gan
Journal:  Front Nutr       Date:  2022-06-30

4.  Identification of prognostic factors for intrahepatic cholangiocarcinoma using long non-coding RNAs-associated ceRNA network.

Authors:  Zhichen Kang; Lixin Guo; Zhuo Zhu; Rongfeng Qu
Journal:  Cancer Cell Int       Date:  2020-07-16       Impact factor: 5.722

5.  Different roles of FAT10, FOXO1, and ADRA2A in hepatocellular carcinoma tumorigenesis in patients with alcoholic steatohepatitis (ASH) vs non-alcoholic steatohepatitis (NASH).

Authors:  Yue Jia; Barbara French; Brittany Tillman; Samuel French
Journal:  Exp Mol Pathol       Date:  2018-07-17       Impact factor: 3.362

6.  Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation.

Authors:  Dongmei Chen; Yufei Yang; Peiying Yang
Journal:  Integr Cancer Ther       Date:  2019 Jan-Dec       Impact factor: 3.279

7.  HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma.

Authors:  Xian Lin; Shi Zuo; Rongcheng Luo; Yonghao Li; Guifang Yu; Yujiao Zou; Yan Zhou; Zhan Liu; Yiyi Liu; Yingying Hu; Yingying Xie; Weiyi Fang; Zhen Liu
Journal:  Theranostics       Date:  2019-10-12       Impact factor: 11.556

8.  Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/β-Catenin Axis.

Authors:  Yanhong Wang; Qian Wang; Xibei Li; Gongwen Luo; Mou Shen; Jia Shi; Xueliang Wang; Lu Tang
Journal:  Drug Des Devel Ther       Date:  2021-01-22       Impact factor: 4.162

9.  Decitabine Induces Change of Biological Traits in Myelodysplastic Syndromes via FOXO1 Activation.

Authors:  Zheng Zhang; Yan Jia; Feng Xv; Lu-Xi Song; Lei Shi; Juan Guo; Chun-Kang Chang
Journal:  Front Genet       Date:  2021-01-27       Impact factor: 4.599

Review 10.  FOXO transcription factor family in cancer and metastasis.

Authors:  Yannasittha Jiramongkol; Eric W-F Lam
Journal:  Cancer Metastasis Rev       Date:  2020-09       Impact factor: 9.264
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