Hualiang Lin1, Yanfei Guo2, Qian Di3, Yang Zheng2, Hong Xian4, Xing Li1, Tao Liu1, Jianpeng Xiao1, Weilin Zeng1, Steven W Howard4, Michael G Vaughn4, Zhengmin Min Qian5, Wenjun Ma6, Fan Wu7. 1. Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. 2. Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, China. 3. Harvard T.H. Chan School of Public Health, Department of Environmental Health, Boston, MA, USA. 4. Saint Louis University College for Public Health & Social Justice, St. Louis, MO, USA. 5. Saint Louis University College for Public Health & Social Justice, St. Louis, MO, USA. Electronic address: zqian2@slu.edu. 6. Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. Electronic address: mawj@gdiph.org.cn. 7. Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, China. Electronic address: wufan@scdc.sh.cn.
Abstract
BACKGROUND: Evidence on the effects of ambient PM2.5 on lung function is limited among adults and the effect modification by dietary fruit and vegetables remains largely unknown. METHODS: We interviewed 29,032 participants aged 50 years and older from the WHO Study on global AGEing and adult health. Annual average PM2.5 levels were estimated for each community using satellite data. We applied multi-level linear regressions to examine the association between ambient PM2.5 and lung function (forced vital capacity (FVC), forced expiratory volume in 1-sec (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF), and forced expiratory flow between 25th and 75th percentiles of FVC (FEF25-75)). RESULTS: We found that ambient PM2.5 was associated with lower lung functions. Each 10μg/m3 increase in PM2.5 corresponded to reductions of 123.58ml in FVC (95% CI: -185.21, -61.95), 126.64ml in FEV1 (95% CI: -186.04, -67.23) and 178.93ml/s FEV25-75 (95% CI: -249.20, -108.66). Lower effect estimates were observed among those with higher consumption of fruit and vegetables. CONCLUSION: Our study suggests that exposure to ambient PM2.5 might be one risk factor of reduced lung function in adults and that higher consumption of fruit and vegetables may mitigate this effect.
BACKGROUND: Evidence on the effects of ambient PM2.5 on lung function is limited among adults and the effect modification by dietary fruit and vegetables remains largely unknown. METHODS: We interviewed 29,032 participants aged 50 years and older from the WHO Study on global AGEing and adult health. Annual average PM2.5 levels were estimated for each community using satellite data. We applied multi-level linear regressions to examine the association between ambient PM2.5 and lung function (forced vital capacity (FVC), forced expiratory volume in 1-sec (FEV1), FEV1/FVC ratio, peak expiratory flow (PEF), and forced expiratory flow between 25th and 75th percentiles of FVC (FEF25-75)). RESULTS: We found that ambient PM2.5 was associated with lower lung functions. Each 10μg/m3 increase in PM2.5 corresponded to reductions of 123.58ml in FVC (95% CI: -185.21, -61.95), 126.64ml in FEV1 (95% CI: -186.04, -67.23) and 178.93ml/s FEV25-75 (95% CI: -249.20, -108.66). Lower effect estimates were observed among those with higher consumption of fruit and vegetables. CONCLUSION: Our study suggests that exposure to ambient PM2.5 might be one risk factor of reduced lung function in adults and that higher consumption of fruit and vegetables may mitigate this effect.
Authors: Wayne R Lawrence; Shao Lin; Ziqiang Lin; Namratha Gurram; Iulia A Neamtiu; Eva Csobod; Eugen Gurzau Journal: Environ Sci Pollut Res Int Date: 2019-12-13 Impact factor: 4.223