| Literature DB >> 28962921 |
Christopher J Law1, Kamela O Alegre2.
Abstract
Multidrug resistance is principally a consequence of the active transport of drugs out of the cell by proteins that are integral membrane transporters. In the following review, we present a synthesis of current understanding of the Escherichia coli multidrug resistance transporter, MdtM, a 410 amino acid residue protein that belongs to the large and ubiquitous major facilitator superfamily (MFS).Entities:
Keywords: Antimicrobial resistance; Drug efflux; Major facilitator superfamily; Membrane protein; Membrane transport; Substrate recognition
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Year: 2017 PMID： 28962921 DOI： 10.1016/j.resmic.2017.09.006
Source DB: PubMed Journal: Res Microbiol ISSN： 0923-2508 Impact factor: 3.992