| Literature DB >> 28962591 |
Ashish M Kamat1, Joaquim Bellmunt2, Matthew D Galsky3, Badrinath R Konety4, Donald L Lamm5, David Langham6, Cheryl T Lee7, Matthew I Milowsky8, Michael A O'Donnell9, Peter H O'Donnell10, Daniel P Petrylak11, Padmanee Sharma12, Eila C Skinner13, Guru Sonpavde14, John A Taylor15, Prasanth Abraham12, Jonathan E Rosenberg16.
Abstract
Entities:
Year: 2017 PMID: 28962591 PMCID: PMC5622592 DOI: 10.1186/s40425-017-0280-z
Source DB: PubMed Journal: J Immunother Cancer ISSN: 2051-1426 Impact factor: 13.751
Fig. 3All of the treatment options shown may be appropriate. The selection of therapy should be individualized based on patient eligibility and the availability of therapy, at the discretion of the treating physician. These algorithms represent the consensus recommendations of the Task Force. (1) Atezolizumab and pembrolizumab are FDA approved for patients with metastatic urothelial carcinoma who are ineligible to receive cisplatin. (2) Atezolizumab, nivolumab, durvalumab, avelumab, and pembrolizumab are FDA approved for advanced disease that has worsened on platinum containing regimens or within 12 months of receiving a platinum-containing regimen before (neoadjuvant) or after surgery (adjuvant). Abbreviations: dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (DDMVAC)