Aleksandra M Gierut1,2, Wanda Niemyska1, Pawel Dabrowski-Tumanski1,3, Piotr Sulkowski4,5, Joanna I Sulkowska1,3. 1. Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, 02-097, Poland. 2. Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Łojasiewicza 11, Cracow, 30-348, Poland. 3. Faculty of Chemistry, University of Warsaw, Pasteura 1, Warsaw, 02-093, Poland. 4. Faculty of Physics, University of Warsaw, Pasteura 5, Warsaw, 02-093, Poland. 5. Walter Burke Institute for Theoretical Physics, California Institute of Technology, Pasadena, CA, 91125, USA.
Abstract
SUMMARY: Entanglement in macromolecules is an important phenomenon and a subject of multidisciplinary research. As recently discovered, around 4% of proteins form new entangled motifs, called lassos. Here we present the PyLasso-a PyMOL plugin to identify and analyse properties of lassos in proteins and other (bio)polymers, as well as in other biological, physical and mathematical systems. The PyLasso is a useful tool for all researchers working on modeling of macromolecules, structure prediction, properties of polymers, entanglement in fluids and fields, etc. AVAILABILITY AND IMPLEMENTATION: The PyLasso and tutorial videos are available at http://pylasso.cent.uw.edu.pl. CONTACT: jsulkowska@cent.uw.edu.pl.
SUMMARY: Entanglement in macromolecules is an important phenomenon and a subject of multidisciplinary research. As recently discovered, around 4% of proteins form new entangled motifs, called lassos. Here we present the PyLasso-a PyMOL plugin to identify and analyse properties of lassos in proteins and other (bio)polymers, as well as in other biological, physical and mathematical systems. The PyLasso is a useful tool for all researchers working on modeling of macromolecules, structure prediction, properties of polymers, entanglement in fluids and fields, etc. AVAILABILITY AND IMPLEMENTATION: The PyLasso and tutorial videos are available at http://pylasso.cent.uw.edu.pl. CONTACT: jsulkowska@cent.uw.edu.pl.
Authors: Ellinor Haglund; Lannie Nguyen; Nicholas Peter Schafer; Heiko Lammert; Patricia Ann Jennings; José Nelson Onuchic Journal: J Biol Chem Date: 2018-06-27 Impact factor: 5.157
Authors: Joanna I Sulkowska; Szymon Niewieczerzal; Aleksandra I Jarmolinska; Jonathan T Siebert; Peter Virnau; Wanda Niemyska Journal: Nucleic Acids Res Date: 2018-07-02 Impact factor: 16.971