Literature DB >> 28959083

Characterization of Continuous and Pulsed Emission modes of a Hybrid Micro Focus X-ray Source for Medical Imaging Applications.

Muhammad U Ghani1, Molly D Wong1, Liqiang Ren1, Di Wu1, Bin Zheng1, John X Rong2, Xizeng Wu3, Hong Liu1.   

Abstract

The aim of this study was to quantitatively characterize a micro focus x-ray tube that can operate in both continuous and pulsed emission modes. The micro focus x-ray source (Model L9181-06, Hamamatsu Photonics, Japan) has a varying focal spot size ranging from 16-50 μm as the source output power changes from 10-39 W. We measured the source output, beam quality, focal spot sizes, kV accuracy, spectra shapes and spatial resolution. Source output was measured using an ionization chamber for various tube voltages (kVs) with varying current (μA) and distances. The beam quality was measured in terms of half value layer (HVL), kV accuracy was measured with a non-invasive kV meter, and the spectra was measured using a compact integrated spectrometer system. The focal spot sizes were measured using a slit method with a CCD detector with a pixel pitch of 22 μm. The spatial resolution was quantitatively measured using the slit method with a CMOS flat panel detector with a 50 μm pixel pitch, and compared to the qualitative results obtained by imaging a contrast bar pattern. The focal spot sizes in the vertical direction were smaller than that of the horizontal direction, the impact of which was visible when comparing the spatial resolution values. Our analyses revealed that both emission modes yield comparable imaging performances in terms of beam quality, spectra shape and spatial resolution effects. There were no significantly large differences, thus providing the motivation for future studies to design and develop stable and robust cone beam imaging systems for various diagnostic applications.

Entities:  

Keywords:  Pulsed beam emission; beam quality; continuous beam; spatial resolution

Year:  2017        PMID: 28959083      PMCID: PMC5612449          DOI: 10.1016/j.nima.2017.02.030

Source DB:  PubMed          Journal:  Nucl Instrum Methods Phys Res A        ISSN: 0168-9002            Impact factor:   1.455


  32 in total

1.  Measurement of focal spot size with slit camera using computed radiography and flat-panel based digital detectors.

Authors:  Xiujiang J Rong; Kerry T Krugh; S Jeff Shepard; William R Geiser
Journal:  Med Phys       Date:  2003-07       Impact factor: 4.071

2.  Medical phase contrast x-ray imaging: current status and future prospects.

Authors:  R A Lewis
Journal:  Phys Med Biol       Date:  2004-08-21       Impact factor: 3.609

3.  A simple method for determining the modulation transfer function in digital radiography.

Authors:  H Fujita; D Y Tsai; T Itoh; K Doi; J Morishita; K Ueda; A Ohtsuka
Journal:  IEEE Trans Med Imaging       Date:  1992       Impact factor: 10.048

Review 4.  In-vitro tomography and non-destructive imaging at depth of pharmaceutical solid dosage forms.

Authors:  J Axel Zeitler; Lynn F Gladden
Journal:  Eur J Pharm Biopharm       Date:  2008-08-22       Impact factor: 5.571

5.  Characterization of a high-energy in-line phase contrast tomosynthesis prototype.

Authors:  Di Wu; Aimin Yan; Yuhua Li; Molly D Wong; Bin Zheng; Xizeng Wu; Hong Liu
Journal:  Med Phys       Date:  2015-05       Impact factor: 4.071

6.  Evolution of spatial resolution in breast CT at UC Davis.

Authors:  Peymon M Gazi; Kai Yang; George W Burkett; Shadi Aminololama-Shakeri; J Anthony Seibert; John M Boone
Journal:  Med Phys       Date:  2015-04       Impact factor: 4.071

7.  Dose and detectability improvements with high energy phase sensitive x-ray imaging in comparison to low energy conventional imaging.

Authors:  Molly Donovan Wong; Aimin Yan; Muhammad Ghani; Yuhua Li; Laurie Fajardo; Xizeng Wu; Hong Liu
Journal:  Phys Med Biol       Date:  2014-04-15       Impact factor: 3.609

8.  Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions.

Authors:  Alexis Broisat; Sophie Hernot; Jakub Toczek; Jens De Vos; Laurent M Riou; Sandrine Martin; Mitra Ahmadi; Nicole Thielens; Ulrich Wernery; Vicky Caveliers; Serge Muyldermans; Tony Lahoutte; Daniel Fagret; Catherine Ghezzi; Nick Devoogdt
Journal:  Circ Res       Date:  2012-03-30       Impact factor: 17.367

9.  Breast specimen radiography: can it predict margin status of excised breast carcinoma?

Authors:  Sarah Goldfeder; Delphine Davis; Jeanne Cullinan
Journal:  Acad Radiol       Date:  2006-12       Impact factor: 3.173

10.  Comparison of Faxitron™ versus MicroCT imaging of the skeleton of the suckling rat.

Authors:  N Powles-Glover; L De Schaepdrijver; J French; J Stewart
Journal:  Reprod Toxicol       Date:  2014-05-09       Impact factor: 3.143

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  1 in total

Review 1.  Tutorial on X-ray photon counting detector characterization.

Authors:  Liqiang Ren; Bin Zheng; Hong Liu
Journal:  J Xray Sci Technol       Date:  2018       Impact factor: 1.535

  1 in total

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