Yanting Wang1,2, Xueyin Mo1,3, Jinglu Zhang4, Yuan Fan1, Kelun Wang4,5, Svensson Peter6,7,8. 1. a Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Department of Endodontics , Affiliated Hospital of Stomatology, Nanjing Medical University , Nanjing , China. 2. b Yixing Institute of Preventive Dentistry , Yixing , China. 3. c Hangzhou ivy dental clinic Co., Limited , Hangzhou , China. 4. d Orofacial Pain & TMD Research Unit, Institute of Stomatology , Affiliated Hospital of Stomatology, Nanjing Medical University , Nanjing , China. 5. e Center for Sensory-Motor Interaction (SMI), Aalborg University , Aalborg , Denmark. 6. f Department of Dentistry and Oral Health, Section of Orofacial Pain and Jaw Function , Aarhus University , Aarhus , Denmark. 7. g Department of Dental Medicine , Karolinska Institutet , Huddinge , Sweden. 8. h Scandinavian Center for Orofacial Neurosciences (SCON) , Aarhus , Denmark.
Abstract
OBJECTIVE: To establish a preliminary thermal and mechanical somatosensory profile using a standardized quantitative sensory testing (QST) to investigate site, gender and age differences in healthy Chinese. MATERIALS AND METHODS: Twenty younger (age: 20-40 years, 10 men, 10 women) and twenty older (age: 41-61 years, 10 men, 10 women) healthy participants completed the study. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical detection threshold (MDT) and mechanical pain threshold (MPT) were measured at five sites: Left hand, bilaterally at the mental area, tip of tongue and the lower lip mucosa. Mixed model ANOVAs with repeated measures were used to analyze the data. RESULTS: MDT(p < .001) and MPT (p < .05) were significantly higher on the hand compared to the mental areas. The CDT ( p = .006) was significantly higher and WDT (p < .001) was significantly lower at the tongue compared to lip mucosa and CDT (p < .001) was higher at the tongue mucosa than at the mental areas. WDT (p < .001) and HPT (p < .05) were significantly higher at the tip of the tongue and the lower lip mucosa compared to the mental areas. Significantly lower sensitivity for WDT (p < .001) and CDT (p = .004) were found in the older group compared to the younger group. Significant gender differences were found with less sensitivity for WDT (p = .024) and MDT (p = .003) in men compared to women. CONCLUSIONS: Application of standardized QST can provide valuable information of orofacial somatosensory phenotypes in a Chinese population. Age, gender and site are mandatory to control for.
OBJECTIVE: To establish a preliminary thermal and mechanical somatosensory profile using a standardized quantitative sensory testing (QST) to investigate site, gender and age differences in healthy Chinese. MATERIALS AND METHODS: Twenty younger (age: 20-40 years, 10 men, 10 women) and twenty older (age: 41-61 years, 10 men, 10 women) healthy participants completed the study. Cold detection threshold (CDT), warm detection threshold (WDT), cold pain threshold (CPT), heat pain threshold (HPT), mechanical detection threshold (MDT) and mechanical pain threshold (MPT) were measured at five sites: Left hand, bilaterally at the mental area, tip of tongue and the lower lip mucosa. Mixed model ANOVAs with repeated measures were used to analyze the data. RESULTS: MDT(p < .001) and MPT (p < .05) were significantly higher on the hand compared to the mental areas. The CDT ( p = .006) was significantly higher and WDT (p < .001) was significantly lower at the tongue compared to lip mucosa and CDT (p < .001) was higher at the tongue mucosa than at the mental areas. WDT (p < .001) and HPT (p < .05) were significantly higher at the tip of the tongue and the lower lip mucosa compared to the mental areas. Significantly lower sensitivity for WDT (p < .001) and CDT (p = .004) were found in the older group compared to the younger group. Significant gender differences were found with less sensitivity for WDT (p = .024) and MDT (p = .003) in men compared to women. CONCLUSIONS: Application of standardized QST can provide valuable information of orofacial somatosensory phenotypes in a Chinese population. Age, gender and site are mandatory to control for.
Entities:
Keywords:
Quantitative sensory testing (QST); age difference; gender difference; somatosensory physiology; trigeminal system
Authors: Ferran Cuenca-Martínez; Elena Bocos-Corredor; África Espinosa-Giménez; Laura Barrero-Santiago; Naira Nefa-Díaz; David Canchal-Crespo; Clovis Varangot-Reille; Aida Herranz-Gómez; Luis Suso-Martí; Núria Sempere-Rubio; Roy La Touche Journal: Int J Environ Res Public Health Date: 2022-09-20 Impact factor: 4.614