Literature DB >> 28957672

Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.

Jonathan Elegheert, Vedrana Cvetkovska, Amber J Clayton, Christina Heroven, Kristel M Vennekens, Samuel N Smukowski, Michael C Regan, Wanyi Jia, Alexandra C Smith, Hiro Furukawa, Jeffrey N Savas, Joris de Wit, Jo Begbie, Ann Marie Craig, A Radu Aricescu.   

Abstract

Entities:  

Year:  2017        PMID: 28957672      PMCID: PMC5625881          DOI: 10.1016/j.neuron.2017.09.011

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


× No keyword cloud information.
(Neuron 95, 896–913; August 16, 2017) After publication, we noticed a number of minor errors within the main text and Figures 1 and 4 that escaped our attention during the proofreading of the manuscript. In the top left panel in Figure 1C, FnIII7 loop C’E is incorrectly labeled as CE. In the legend to Figure 3A, the buried surface area of Site II is incorrectly stated as 859 Å2, while the correct value is 1,000 Å2. In Figure 4B, residue Glu294 (E294) is incorrectly labeled as Asp294 (D294). This error is also present in the main text paragraph “MDGA and NRX Share Binding Interfaces on NL.” The errors have no effect on any of the conclusions in the paper, and the main text and Figures 1 and 4 have now been corrected online. The authors apologize for any confusion the errors may have caused.
Figure 1C

Crystal Structure of MDGA1 (corrected)

Figure 4B

MDGA and NRX Compete for Binding to the NL Site I Interface (corrected)

Crystal Structure of MDGA1 (corrected) Crystal Structure of MDGA1 (original) MDGA and NRX Compete for Binding to the NL Site I Interface (corrected) MDGA and NRX Compete for Binding to the NL Site I Interface (original)
  5 in total

1.  Refining the Roles of Neuroligins in Synapse Development and Function: A Reductionist Conditional Knock-out Approach.

Authors:  Hunter S Shaw; Christopher K Salmon
Journal:  J Neurosci       Date:  2017-12-06       Impact factor: 6.167

Review 2.  The dark side of synaptic proteins in tumours.

Authors:  Jing Li; Yalan Xu; Hai Zhu; Yin Wang; Peifeng Li; Dong Wang
Journal:  Br J Cancer       Date:  2022-05-27       Impact factor: 9.075

Review 3.  Towards an Understanding of Synapse Formation.

Authors:  Thomas C Südhof
Journal:  Neuron       Date:  2018-10-24       Impact factor: 17.173

4.  The γ-Protocadherins Interact Physically and Functionally with Neuroligin-2 to Negatively Regulate Inhibitory Synapse Density and Are Required for Normal Social Interaction.

Authors:  David M Steffen; Sarah L Ferri; Charles G Marcucci; Kelsey L Blocklinger; Michael J Molumby; Ted Abel; Joshua A Weiner
Journal:  Mol Neurobiol       Date:  2021-01-20       Impact factor: 5.682

5.  Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health.

Authors:  Sen Yin; Xuemei Bai; Danqing Xin; Tingting Li; Xili Chu; Hongfei Ke; Min Han; Wenqiang Chen; Xingang Li; Zhen Wang
Journal:  Neural Plast       Date:  2020-08-01       Impact factor: 3.599

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.