Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation.

Literature DB >> 28956686

G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation.

Francesco Casciello^1,2, Jason S Lee^1,2.

Abstract

Entities: Disease Gene

Keywords: G9a; epigenetic regulation; histone methylation; patient stratification; tumor hypoxia

Mesh：

Year: 2017 PMID： 28956686 PMCID： PMC5731417 DOI： 10.1080/15384101.2017.1377505

Source DB: PubMed Journal: Cell Cycle ISSN： 1551-4005 Impact factor: 4.534

× No keyword cloud information.

7 in total

1. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.

Authors: Francesco Casciello; Fares Al-Ejeh; Greg Kelly; Donal J Brennan; Shin Foong Ngiow; Arabella Young; Thomas Stoll; Karolina Windloch; Michelle M Hill; Mark J Smyth; Frank Gannon; Jason S Lee
Journal: Proc Natl Acad Sci U S A Date: 2017-06-19 Impact factor: 11.205

2. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.

Authors: Haobin Chen; Yan Yan; Todd L Davidson; Yoichi Shinkai; Max Costa
Journal: Cancer Res Date: 2006-09-15 Impact factor: 12.701

3. Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

Authors: Makoto Tachibana; Jun Ueda; Mikiko Fukuda; Naoki Takeda; Tsutomu Ohta; Hiroko Iwanari; Toshiko Sakihama; Tatsuhiko Kodama; Takao Hamakubo; Yoichi Shinkai
Journal: Genes Dev Date: 2005-03-17 Impact factor: 11.361

4. Hypoxia-induced methylation of a pontin chromatin remodeling factor.

Authors: Jason S Lee; Yunho Kim; Jinhyuk Bhin; Hi-Jai R Shin; Hye Jin Nam; Seung Hoon Lee; Jong-Bok Yoon; Olivier Binda; Or Gozani; Daehee Hwang; Sung Hee Baek
Journal: Proc Natl Acad Sci U S A Date: 2011-08-08 Impact factor: 11.205

5. Negative regulation of hypoxic responses via induced Reptin methylation.

Authors: Jason S Lee; Yunho Kim; Ik Soo Kim; Bogyou Kim; Hee June Choi; Ji Min Lee; Hi-Jai R Shin; Jung Hwa Kim; Ji-Young Kim; Sang-Beom Seo; Ho Lee; Olivier Binda; Or Gozani; Gregg L Semenza; Minhyung Kim; Keun Il Kim; Daehee Hwang; Sung Hee Baek
Journal: Mol Cell Date: 2010-07-09 Impact factor: 17.970

6. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.

Authors: Makoto Tachibana; Kenji Sugimoto; Masami Nozaki; Jun Ueda; Tsutomu Ohta; Misao Ohki; Mikiko Fukuda; Naoki Takeda; Hiroyuki Niida; Hiroyuki Kato; Yoichi Shinkai
Journal: Genes Dev Date: 2002-07-15 Impact factor: 11.361

Review 7. Functional Role of G9a Histone Methyltransferase in Cancer.

Authors: Francesco Casciello; Karolina Windloch; Frank Gannon; Jason S Lee
Journal: Front Immunol Date: 2015-09-25 Impact factor: 7.561

7 in total

4 in total

G9a in hypoxia: Linking tumor hypoxia and epigenetic regulation.

1. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.

2. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.

3. Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9.

4. Hypoxia-induced methylation of a pontin chromatin remodeling factor.

5. Negative regulation of hypoxic responses via induced Reptin methylation.

6. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.

Review 7. Functional Role of G9a Histone Methyltransferase in Cancer.

Review 1. Intratumoral Heterogeneity: More Than Just Mutations.

2. Genome-wide analysis of the hypoxia-related DNA methylation-driven genes in lung adenocarcinoma progression.

Review 3. RUNX Family in Hypoxic Microenvironment and Angiogenesis in Cancers.

4. PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells.