Literature DB >> 28954808

Protease-Activated Receptor-1 Signaling: The Big Picture.

Robert Flaumenhaft1.   

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Year:  2017        PMID： 28954808      PMCID： PMC5714320          DOI： 10.1161/ATVBAHA.117.310068

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


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  11 in total

1.  Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

Authors:  Joseph N McLaughlin; Lixin Shen; Michael Holinstat; Joshua D Brooks; Emmanuele Dibenedetto; Heidi E Hamm
Journal:  J Biol Chem       Date:  2005-05-04       Impact factor: 5.157

2.  Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

Authors:  T K Vu; D T Hung; V I Wheaton; S R Coughlin
Journal:  Cell       Date:  1991-03-22       Impact factor: 41.582

3.  Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1.

Authors:  Louisa Dowal; Derek S Sim; James R Dilks; Price Blair; Sarah Beaudry; Bradley M Denker; Georgios Koukos; Athan Kuliopulos; Robert Flaumenhaft
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

4.  Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar.

Authors:  Omozuanvbo Aisiku; Christian G Peters; Karen De Ceunynck; Chandra C Ghosh; James R Dilks; Susanna F Fustolo-Gunnink; Mingdong Huang; Chris Dockendorff; Samir M Parikh; Robert Flaumenhaft
Journal:  Blood       Date:  2015-01-13       Impact factor: 22.113

5.  Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds.

Authors:  Unice J K Soh; JoAnn Trejo
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-21       Impact factor: 11.205

6.  Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46.

Authors:  Laurent O Mosnier; Ranjeet K Sinha; Laurent Burnier; Eveline A Bouwens; John H Griffin
Journal:  Blood       Date:  2012-11-13       Impact factor: 22.113

7.  Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.

Authors:  Bart L van den Eshof; Arie J Hoogendijk; Pelle J Simpson; Floris P J van Alphen; Sara Zanivan; Koen Mertens; Alexander B Meijer; Maartje van den Biggelaar
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-08-17       Impact factor: 8.311

Review 8.  Targeting PAR1: Now What?

Authors:  Robert Flaumenhaft; Karen De Ceunynck
Journal:  Trends Pharmacol Sci       Date:  2017-05-27       Impact factor: 14.819

9.  Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor.

Authors:  Chris Dockendorff; Omozuanvbo Aisiku; Lynn Verplank; James R Dilks; Daniel A Smith; Susanna F Gunnink; Louisa Dowal; Joseph Negri; Michelle Palmer; Lawrence Macpherson; Stuart L Schreiber; Robert Flaumenhaft
Journal:  ACS Med Chem Lett       Date:  2012-01-30       Impact factor: 4.345

10.  High-resolution crystal structure of human protease-activated receptor 1.

Authors:  Cheng Zhang; Yoga Srinivasan; Daniel H Arlow; Juan Jose Fung; Daniel Palmer; Yaowu Zheng; Hillary F Green; Anjali Pandey; Ron O Dror; David E Shaw; William I Weis; Shaun R Coughlin; Brian K Kobilka
Journal:  Nature       Date:  2012-12-09       Impact factor: 49.962
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  2 in total

1.  Protease Activity in Vascular Disease.

Authors:  Megan A Slack; Scott M Gordon
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-09-25       Impact factor: 8.311

Review 2.  The domino effect triggered by the tethered ligand of the protease activated receptors.

Authors:  Xu Han; Marvin T Nieman
Journal:  Thromb Res       Date:  2020-08-04       Impact factor: 3.944
  2 in total

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