Literature DB >> 28953879

Obesity: Receptors identified for a weight regulator.

Mart Saarma1, Adrian Goldman2.   

Abstract

Mesh：

Year:  2017        PMID： 28953879     DOI： 10.1038/nature24143

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  18 in total

1.  Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15.

Authors:  Jer-Yuan Hsu; Suzanne Crawley; Michael Chen; Dina A Ayupova; Darrin A Lindhout; Jared Higbee; Alan Kutach; William Joo; Zhengyu Gao; Diana Fu; Carmen To; Kalyani Mondal; Betty Li; Avantika Kekatpure; Marilyn Wang; Teresa Laird; Geoffrey Horner; Jackie Chan; Michele McEntee; Manuel Lopez; Damodharan Lakshminarasimhan; Andre White; Sheng-Ping Wang; Jun Yao; Junming Yie; Hugo Matern; Mark Solloway; Raj Haldankar; Thomas Parsons; Jie Tang; Wenyan D Shen; Yu Alice Chen; Hui Tian; Bernard B Allan
Journal:  Nature       Date:  2017-09-27       Impact factor: 49.962

2.  Identification, expression and functional characterization of the GRAL gene.

Authors:  Zhihua Li; Bingwei Wang; Xuefei Wu; Shi-Yuan Cheng; Luminita Paraoan; Jiawei Zhou
Journal:  J Neurochem       Date:  2005-08-08       Impact factor: 5.372

3.  GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.

Authors:  Linda Yang; Chih-Chuan Chang; Zhe Sun; Dennis Madsen; Haisun Zhu; Søren B Padkjær; Xiaoai Wu; Tao Huang; Karin Hultman; Sarah J Paulsen; Jishu Wang; Anne Bugge; Jane Boesen Frantzen; Per Nørgaard; Jacob Fuglsbjerg Jeppesen; Zhiru Yang; Anna Secher; Haibin Chen; Xun Li; Linu Mary John; Bing Shan; Zhenhua He; Xiang Gao; Jing Su; Kristian T Hansen; Wei Yang; Sebastian Beck Jørgensen
Journal:  Nat Med       Date:  2017-08-28       Impact factor: 53.440

Review 4.  The GDNF family: signalling, biological functions and therapeutic value.

Authors:  Matti S Airaksinen; Mart Saarma
Journal:  Nat Rev Neurosci       Date:  2002-05       Impact factor: 34.870

5.  Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

Authors:  Heiko Johnen; Shu Lin; Tamara Kuffner; David A Brown; Vicky Wang-Wei Tsai; Asne R Bauskin; Liyun Wu; Greg Pankhurst; Lele Jiang; Simon Junankar; Mark Hunter; W Douglas Fairlie; Nicola J Lee; Ronaldo F Enriquez; Paul A Baldock; Eva Corey; Fred S Apple; Maryann M Murakami; En-Ju Lin; Chuansong Wang; Matthew J During; Amanda Sainsbury; Herbert Herzog; Samuel N Breit
Journal:  Nat Med       Date:  2007-11-04       Impact factor: 53.440

6.  The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding.

Authors:  Vimal Parkash; Veli-Matti Leppänen; Heidi Virtanen; Jaana M Jurvansuu; Maxim M Bespalov; Yulia A Sidorova; Pia Runeberg-Roos; Mart Saarma; Adrian Goldman
Journal:  J Biol Chem       Date:  2008-10-08       Impact factor: 5.157

Review 7.  The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1.

Authors:  Klaus Unsicker; Björn Spittau; Kerstin Krieglstein
Journal:  Cytokine Growth Factor Rev       Date:  2013-06-18       Impact factor: 7.638

8.  Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets.

Authors:  Laurence Macia; Vicky Wang-Wei Tsai; Amy D Nguyen; Heiko Johnen; Tamara Kuffner; Yan-Chuan Shi; Shu Lin; Herbert Herzog; David A Brown; Samuel N Breit; Amanda Sainsbury
Journal:  PLoS One       Date:  2012-04-13       Impact factor: 3.240

9.  Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system.

Authors:  Edgar R Kramer; Liviu Aron; Geert M J Ramakers; Sabine Seitz; Xiaoxi Zhuang; Klaus Beyer; Marten P Smidt; Rüdiger Klein
Journal:  PLoS Biol       Date:  2007-03       Impact factor: 8.029

10.  Genetic identification of a neural circuit that suppresses appetite.

Authors:  Matthew E Carter; Marta E Soden; Larry S Zweifel; Richard D Palmiter
Journal:  Nature       Date:  2013-10-13       Impact factor: 49.962
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  6 in total

1.  Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice.

Authors:  Emily J Onufer; Shirli Tay; Lauren K Barron; Cathleen M Courtney; Brad W Warner; Jun Guo
Journal:  Biochem Biophys Res Commun       Date:  2018-10-12       Impact factor: 3.575

Review 2.  Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia.

Authors:  Jawed Akhtar Siddiqui; Ramesh Pothuraju; Parvez Khan; Gunjan Sharma; Sakthivel Muniyan; Parthasarathy Seshacharyulu; Maneesh Jain; Mohd Wasim Nasser; Surinder Kumar Batra
Journal:  Cytokine Growth Factor Rev       Date:  2021-11-17       Impact factor: 7.638

3.  CDNF Protein Therapy in Parkinson's Disease.

Authors:  Henri J Huttunen; Mart Saarma
Journal:  Cell Transplant       Date:  2019-04-04       Impact factor: 4.064

4.  Failure of Glial Cell-Line Derived Neurotrophic Factor (GDNF) in Clinical Trials Orchestrated By Reduced NR4A2 (NURR1) Transcription Factor in Parkinson's Disease. A Systematic Review.

Authors:  Piniel Alphayo Kambey; Kouminin Kanwore; Abiola Abdulrahman Ayanlaja; Iqra Nadeem; YinZhen Du; Wokuheleza Buberwa; WenYa Liu; Dianshuai Gao
Journal:  Front Aging Neurosci       Date:  2021-02-24       Impact factor: 5.750

Review 5.  Small Molecules and Peptides Targeting Glial Cell Line-Derived Neurotrophic Factor Receptors for the Treatment of Neurodegeneration.

Authors:  Yulia A Sidorova; Mart Saarma
Journal:  Int J Mol Sci       Date:  2020-09-08       Impact factor: 5.923

6.  Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats.

Authors:  Juho-Matti Renko; Arun Kumar Mahato; Tanel Visnapuu; Konsta Valkonen; Mati Karelson; Merja H Voutilainen; Mart Saarma; Raimo K Tuominen; Yulia A Sidorova
Journal:  J Parkinsons Dis       Date:  2021       Impact factor: 5.568
  6 in total

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