Andrea Ciavattini1, Nicolò Clemente, Carlo Antonio Liverani, Paolo Cattani, Luca Giannella, Giovanni Delli Carpini, Stefano Morini, Monica Buttignol, Francesco Sopracordevole. 1. 1Woman's Health Sciences Department, Gynecologic Section, Università Politecnica delle Marche, Ancona, Italy; 2Gynecologic Oncology Unit, Department. of Obstetrics & Gynecology Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, University of Milano, Milan, Italy; 3Center for Gynecologic Oncology Prevention, AULSS 20, Verona, Italy; 4Local Health Authority of Reggio Emilia, Division of Obstetrics and Gynecology, Cesare Magati Hospital, Scandiano, Italy; and 5Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy.
Abstract
OBJECTIVES: The aim of the present study was to observe the trend of length of cone excisions in women treated with cervical excision procedure in five institutions of Central and Northern Italy. MATERIALS AND METHODS: A multicenter retrospective cohort study was conducted on women who underwent a cervical excision procedure between January 2006 and December 2014. The pertinent clinical, histopathological, and sociodemographic characteristics of each woman were collected. In particular, the length of the cone specimen was evaluated and all of the factors that potentially influenced the length of excision were considered. RESULTS: A total of 1482 women who underwent a cervical excision procedure from January 2006 to December 2014 were included. A mean (SD) cone length of 12.9 (5.0) mm was reported, and mostly, a significant decrease during the whole study period emerged. Age (r = 0.1, p = .007) and preoperative diagnosis of glandular lesions (r = 0.1, p < .001) were significantly related to the length of cone excision on multivariate analysis. Compared with the carbon dioxide laser excisional procedure, loop electrosurgical excision procedure showed a negative correlation with the length of excision (r = -0.2, p < .001). CONCLUSIONS: During the study period, a significant decrease in the length of cone excision was observed, probably reflecting the gynecologists' acquired awareness of the increased risk of adverse obstetric outcomes for future pregnancies in the case of wide cone excisions.
OBJECTIVES: The aim of the present study was to observe the trend of length of cone excisions in women treated with cervical excision procedure in five institutions of Central and Northern Italy. MATERIALS AND METHODS: A multicenter retrospective cohort study was conducted on women who underwent a cervical excision procedure between January 2006 and December 2014. The pertinent clinical, histopathological, and sociodemographic characteristics of each woman were collected. In particular, the length of the cone specimen was evaluated and all of the factors that potentially influenced the length of excision were considered. RESULTS: A total of 1482 women who underwent a cervical excision procedure from January 2006 to December 2014 were included. A mean (SD) cone length of 12.9 (5.0) mm was reported, and mostly, a significant decrease during the whole study period emerged. Age (r = 0.1, p = .007) and preoperative diagnosis of glandular lesions (r = 0.1, p < .001) were significantly related to the length of cone excision on multivariate analysis. Compared with the carbon dioxide laser excisional procedure, loop electrosurgical excision procedure showed a negative correlation with the length of excision (r = -0.2, p < .001). CONCLUSIONS: During the study period, a significant decrease in the length of cone excision was observed, probably reflecting the gynecologists' acquired awareness of the increased risk of adverse obstetric outcomes for future pregnancies in the case of wide cone excisions.
Authors: Andrea Ciavattini; Matteo Serri; Jacopo Di Giuseppe; Carlo Antonio Liverani; Barbara Gardella; Maria Papiccio; Giovanni Delli Carpini; Stefano Morini; Nicolò Clemente; Francesco Sopracordevole Journal: BMJ Open Date: 2019-07-03 Impact factor: 2.692
Authors: Francesco Sopracordevole; Nicolò Clemente; Maria Papiccio; Anna Del Fabro; Matteo Serri; Mariasole Fichera; Monica Buttignol; Giorgio Giorda; Giovanni Delli Carpini; Andrea Ciavattini Journal: Medicine (Baltimore) Date: 2022-07-22 Impact factor: 1.817