Balasubramaniam Balakumar1, Sangeet Gangadharan1, Nithya Ponmudi2, Satish Kumar2, John Jude Prakash3, Thomas Palocaren4. 1. Paediatric Orthopaedic Unit, Christian Medical College, Vellore, 632004, India. 2. Dept of Child Health, Christian Medical College, Vellore, 632004, India. 3. Dept of Microbiology, Christian Medical College, Vellore, 632004, India. 4. Paediatric Orthopaedic Unit, Christian Medical College, Ida scudder Road, Vellore, 632004, India.
Abstract
OBJECTIVE: Salmonella osteomyelitis in immunocompromised individuals with sickle cell anaemia is well documented. Its occurrence in immunocompetent children is rare. METHODS: All pus culture positive cases of salmonella typhi between the period 2009 to 2014 were reviewed and only those children without sickle cell disease or trait were considered further. RESULTS: Eighty five patients had positive cultures. Of these only three children had culture positive Salmonella septic arthritis in the absence of sickle cell disease. Two children had shoulder septic arthritis while one had hip septic arthritis. CONCLUSION: Our case series highlights the possibility of salmonella typhi osteomyelitis in immunocompetent individuals. Clinicians should be aware of this presentation which is usually delayed due to the atypical organism and lack of clinical response in the initial stages, as disastrous sequelae of septic arthritis may result if prompt treatment is not initiated in time.
OBJECTIVE:Salmonella osteomyelitis in immunocompromised individuals with sickle cell anaemia is well documented. Its occurrence in immunocompetent children is rare. METHODS: All pus culture positive cases of salmonella typhi between the period 2009 to 2014 were reviewed and only those children without sickle cell disease or trait were considered further. RESULTS: Eighty five patients had positive cultures. Of these only three children had culture positive Salmonella septic arthritis in the absence of sickle cell disease. Two children had shoulder septic arthritis while one had hip septic arthritis. CONCLUSION: Our case series highlights the possibility of salmonella typhi osteomyelitis in immunocompetent individuals. Clinicians should be aware of this presentation which is usually delayed due to the atypical organism and lack of clinical response in the initial stages, as disastrous sequelae of septic arthritis may result if prompt treatment is not initiated in time.
Authors: Ana Lucia L Lima; Priscila R Oliveira; Vladimir C Carvalho; Sergio Cimerman; Eduardo Savio Journal: Braz J Infect Dis Date: 2014-04-01 Impact factor: 3.257
Authors: Andrzej Krzysztofiak; Marco Roversi; Antonio Musolino; Marco Cirillo; Renato Maria Toniolo; Osvaldo Mazza; Livia Gargiullo; Laura Lancella; Paolo Rossi; Alberto Villani Journal: Sci Rep Date: 2022-09-01 Impact factor: 4.996