G B Halmos1, L Bras1,2, S Siesling3,4, B F A M van der Laan1, J A Langendijk5, B A C van Dijk3,6. 1. Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. 2. Graduate School of Medical Sciences (Damage and Repair in Cancer Development and Cancer Treatment), University of Groningen, Groningen, The Netherlands. 3. Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands. 4. Department of Health Technology and Services Research, MIRA Institute for Technical Medicine and Biomedical Technology, University of Twente, Enschede, The Netherlands. 5. Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. 6. Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Abstract
OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups. DESIGN: Cohort study. SETTING: Netherlands Cancer Registry. PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorised into different age groups. MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment. RESULTS: The study population was composed of 11 558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six per cent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (eg oral cavity: 17% in 80+ vs 34% in 60-; P < .001). The percentage of patients not receiving tumour-directed treatment increased with age (eg oropharyngeal cancer: 25% in 80+ vs 6% in 80-; P < .001). CONCLUSIONS: This study confirms that less multimodal and tumour-directed treatment is applied with the increasing age of head and neck cancer patients.
OBJECTIVES: To explore the incidence and treatment pattern of head and neck cancer in different age groups. DESIGN: Cohort study. SETTING: Netherlands Cancer Registry. PARTICIPANTS: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorised into different age groups. MAIN OUTCOME MEASURES: Tumour site, stage, treatment modality, location of diagnosis and treatment. RESULTS: The study population was composed of 11 558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six per cent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (eg oral cavity: 17% in 80+ vs 34% in 60-; P < .001). The percentage of patients not receiving tumour-directed treatment increased with age (eg oropharyngeal cancer: 25% in 80+ vs 6% in 80-; P < .001). CONCLUSIONS: This study confirms that less multimodal and tumour-directed treatment is applied with the increasing age of head and neck cancerpatients.
Authors: Lidia S van Huizen; Pieter Dijkstra; Gyorgy B Halmos; Johanna G M van den Hoek; Klaas T van der Laan; Oda B Wijers; Kees Ahaus; Jan G A M de Visscher; Jan Roodenburg Journal: BMJ Open Date: 2019-11-07 Impact factor: 2.692
Authors: Linda Bras; Daphne A J J Driessen; Julius de Vries; Suzanne Festen; Bernard F A M van der Laan; Barbara L van Leeuwen; Geertruida H de Bock; Gyorgy B Halmos Journal: Eur J Cancer Care (Engl) Date: 2019-09-30 Impact factor: 2.520
Authors: Behrooz Ziad Alizadeh; Johannes Albertus Langendijk; Elnaz Naderi; Anne Petra Gerarda Crijns; Roel Johannes Henricus Marinus Steenbakkers; Johanna Geertruida Maria van den Hoek; Hendrika Marike Boezen Journal: J Transl Med Date: 2021-11-27 Impact factor: 5.531