OBJECTIVE: Brain-machine interface training was developed for upper-extremity rehabilitation for patients with severe hemiparesis. Its clinical application, however, has been limited because of its lack of feasibility in real-world rehabilitation settings. We developed a new compact task-specific brain-machine interface system that enables task-specific training, including reach-and-grasp tasks, and studied its clinical feasibility and effectiveness for upper-extremity motor paralysis in patients with stroke. DESIGN: Prospective beforeâ€"after study. SUBJECTS: Twenty-six patients with severe chronic hemiparetic stroke. METHODS: Participants were trained with the brain-machine interface system to pick up and release pegs during 40-min sessions and 40 min of standard occupational therapy per day for 10 days. Fugl-Meyer upper-extremity motor (FMA) and Motor Activity Log-14 amount of use (MAL-AOU) scores were assessed before and after the intervention. To test its feasibility, 4 occupational therapists who operated the system for the first time assessed it with the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST) 2.0. RESULTS: FMA and MAL-AOU scores improved significantly after brain-machine interface training, with the effect sizes being medium and large, respectively (p<0.01, d=0.55; p<0.01, d=0.88). QUEST effectiveness and safety scores showed feasibility and satisfaction in the clinical setting. CONCLUSION: Our newly developed compact brain-machine interface system is feasible for use in real-world clinical settings.
OBJECTIVE: Brain-machine interface training was developed for upper-extremity rehabilitation for patients with severe hemiparesis. Its clinical application, however, has been limited because of its lack of feasibility in real-world rehabilitation settings. We developed a new compact task-specific brain-machine interface system that enables task-specific training, including reach-and-grasp tasks, and studied its clinical feasibility and effectiveness for upper-extremity motor paralysis in patients with stroke. DESIGN: Prospective beforeâ€"after study. SUBJECTS: Twenty-six patients with severe chronic hemiparetic stroke. METHODS:Participants were trained with the brain-machine interface system to pick up and release pegs during 40-min sessions and 40 min of standard occupational therapy per day for 10 days. Fugl-Meyer upper-extremity motor (FMA) and Motor Activity Log-14 amount of use (MAL-AOU) scores were assessed before and after the intervention. To test its feasibility, 4 occupational therapists who operated the system for the first time assessed it with the Quebec User Evaluation of Satisfaction with assistive Technology (QUEST) 2.0. RESULTS: FMA and MAL-AOU scores improved significantly after brain-machine interface training, with the effect sizes being medium and large, respectively (p<0.01, d=0.55; p<0.01, d=0.88). QUEST effectiveness and safety scores showed feasibility and satisfaction in the clinical setting. CONCLUSION: Our newly developed compact brain-machine interface system is feasible for use in real-world clinical settings.
Authors: Mary Ellen Stoykov; Erin King; Fabian J David; Amanda Vatinno; Louis Fogg; Daniel M Corcos Journal: Restor Neurol Neurosci Date: 2020 Impact factor: 2.406
Authors: Alexander B Remsik; Peter L E van Kan; Shawna Gloe; Klevest Gjini; Leroy Williams; Veena Nair; Kristin Caldera; Justin C Williams; Vivek Prabhakaran Journal: Front Hum Neurosci Date: 2022-07-06 Impact factor: 3.473