Literature DB >> 28949179

Mechanism for Mechanical Wave Break in the Heart Muscle.

L D Weise1,2, A V Panfilov1.   

Abstract

Using a reaction-diffusion-mechanics model we identify a mechanism for mechanical wave break in the heart muscle. For a wide range of strengths and durations an external mechanical load causes wave front dissipation leading to formation and breakup of spiral waves. We explain the mechanism, and discuss under which conditions it can cause or abolish cardiac arrhythmias.

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Year:  2017        PMID: 28949179     DOI: 10.1103/PhysRevLett.119.108101

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  3 in total

1.  A Simulation Study of the Role of Mechanical Stretch in Arrhythmogenesis during Cardiac Alternans.

Authors:  Azzam Hazim; Youssef Belhamadia; Stevan Dubljevic
Journal:  Biophys J       Date:  2020-11-26       Impact factor: 4.033

2.  Delayed global feedback in the genesis and stability of spatiotemporal excitation patterns in paced biological excitable media.

Authors:  Zhen Song; Zhilin Qu
Journal:  PLoS Comput Biol       Date:  2020-10-05       Impact factor: 4.475

3.  A survey of pathways for mechano-electric coupling in the atria.

Authors:  Aditi Roy; Jack Lee
Journal:  Prog Biophys Mol Biol       Date:  2020-10-11       Impact factor: 3.667

  3 in total

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