Amelia Tan1, Sandra Lowe1,2, Amanda Henry1,3,4. 1. School of Women's and Children's Health, UNSW Medicine, Sydney, NSW, Australia. 2. Department of Obstetrics, Royal Hospital for Women, Randwick, NSW, Australia. 3. Department of Maternal-Fetal Medicine, Royal Hospital for Women, Randwick, NSW, Australia. 4. Women's and Children's Health, St George Hospital, Kogarah, NSW, Australia.
Abstract
AIMS: To investigate the effect of nausea and vomiting of pregnancy (NVP) on quality of life (QoL) and activities of daily living/socioeconomic function in a contemporary Australian setting. MATERIALS AND METHODS: Observational, single centre prospective cohort study using validated survey instruments in pregnant women at 9-16 weeks gestation at a tertiary metropolitan women's hospital in Sydney, Australia. QoL measured by the Short-Form Health Survey (SF-12) was compared between those with and without NVP. NVP severity scores were correlated with QoL scores, work patterns and medication use. RESULTS: Of 116 participants, 72% had NVP, with no baseline (including mental health) differences between women with or without NVP. As classified by modified Pregnancy-Unique-Quantified-Emesis (PUQE) survey, 42% had mild symptoms, 55% moderate and 1% severe. SF-12 Physical Component Summary (PCS) scores were significantly lower for those with NVP (P < 0.001), but not Mental Component Summary (MCS) scores (P = 0.11). Decreasing QoL was associated with increasing NVP severity (P < 0.001), most markedly in the physical domain (P < 0.001). Only 39% of women used any NVP treatment and 15% pharmacotherapy. Most used treatments were vitamin B6 , ginger, metoclopramide and natural remedies. Significantly more women with NVP required time off work (45% vs 16%, P = 0.003). CONCLUSIONS: NVP is a physically morbid disease, affecting most pregnancies. NVP has a significant detrimental impact on QoL, especially physical QoL and work function. Despite this, we found low treatment utilisation, even in those with moderate/severe symptoms. Women should be encouraged to seek assistance for NVP and further education is required to improve practitioner awareness and management.
AIMS: To investigate the effect of nausea and vomiting of pregnancy (NVP) on quality of life (QoL) and activities of daily living/socioeconomic function in a contemporary Australian setting. MATERIALS AND METHODS: Observational, single centre prospective cohort study using validated survey instruments in pregnant women at 9-16 weeks gestation at a tertiary metropolitan women's hospital in Sydney, Australia. QoL measured by the Short-Form Health Survey (SF-12) was compared between those with and without NVP. NVP severity scores were correlated with QoL scores, work patterns and medication use. RESULTS: Of 116 participants, 72% had NVP, with no baseline (including mental health) differences between women with or without NVP. As classified by modified Pregnancy-Unique-Quantified-Emesis (PUQE) survey, 42% had mild symptoms, 55% moderate and 1% severe. SF-12 Physical Component Summary (PCS) scores were significantly lower for those with NVP (P < 0.001), but not Mental Component Summary (MCS) scores (P = 0.11). Decreasing QoL was associated with increasing NVP severity (P < 0.001), most markedly in the physical domain (P < 0.001). Only 39% of women used any NVP treatment and 15% pharmacotherapy. Most used treatments were vitamin B6 , ginger, metoclopramide and natural remedies. Significantly more women with NVP required time off work (45% vs 16%, P = 0.003). CONCLUSIONS: NVP is a physically morbid disease, affecting most pregnancies. NVP has a significant detrimental impact on QoL, especially physical QoL and work function. Despite this, we found low treatment utilisation, even in those with moderate/severe symptoms. Women should be encouraged to seek assistance for NVP and further education is required to improve practitioner awareness and management.
Authors: Tien V Tran; Hoang C Nguyen; Linh V Pham; Minh H Nguyen; Huu Cong Nguyen; Tung H Ha; Dung T Phan; Hung K Dao; Phuoc B Nguyen; Manh V Trinh; Thinh V Do; Hung Q Nguyen; Thao T P Nguyen; Nhan P T Nguyen; Cuong Q Tran; Khanh V Tran; Trang T Duong; Hai X Pham; Lam V Nguyen; Tam T Vo; Binh N Do; Thai H Duong; Minh Khue Pham; Thu T M Pham; Kien Trung Nguyen; Shwu-Huey Yang; Jane C J Chao; Tuyen Van Duong Journal: BMJ Open Date: 2020-12-07 Impact factor: 2.692
Authors: Ching-Fang Lee; Fur-Hsing Wen; Yvonne Hsiung; Jian-Pei Huang; Chun-Wei Chang; Hung-Hui Chen Journal: Int J Environ Res Public Health Date: 2021-06-11 Impact factor: 3.390