Yanina Zócalo1, Santiago Curcio2, Victoria García-Espinosa2, Pedro Chiesa3, Gustavo Giachetto4, Daniel Bia2. 1. Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800, Montevideo, Uruguay. yana@fmed.edu.uy. 2. Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800, Montevideo, Uruguay. 3. Servicio de Cardiología Pediátrica, Centro Hospitalario Pereira Rossell, ASSE-Ministry of Public Health, Boulevard Artigas 1550, 11600, Montevideo, Uruguay. 4. Clínica Pediátrica "C", Centro Hospitalario Pereira Rossell, ASSE, Republic University, Boulevard Artigas 1550, 11600, Montevideo, Uruguay.
Abstract
INTRODUCTION: The association between arterial parameters and blood pressure (BP) interindividual variations could depend on the arterial segment, BP component (systolic, SBP; diastolic, DBP; pulse pressure, PP) and/or on whether central (cBP) or peripheral (pBP) BP variations are considered. AIM: To assess and compare arterial parameters variations associated with interindividual variations in cBP and pBP. METHODS: Healthy subjects (n = 923; 488 males, 2-84 years) were included. pBP and cBP waves were obtained (Mobil-O-Graph; SphygmoCor). Arterial diameter, intima-media thickness, local elastic modulus (carotid, CEM; brachial, BEM; femoral, FEM) and regional (carotid-radial and carotid-femoral pulse wave velocity; crPWV and cfPWV) arterial stiffness were determined. Associations between BP and arterial parameters interindividual variations were analyzed and compared (correlations; linear regressions; slopes comparisons) considering data transformed into z-scores. RESULTS: Given a variation in z-cSBP or z-pSBP, z-CEM, z-FEM and z-cfPWV (stiffness indexes), were among the parameters with major BP-associated variations. z-crPWV and z-cfPWV, rather than local stiffness indexes were the parameters with major variations associated with z-DBP variations. z-cPP or z-pPP were associated with z-CEM and z-FEM variations, but not with brachial or regional stiffness variations. Most of the arterial parameters-BP slopes did not show significant differences when considering a variation in z-cSBP and z-pSBP. z-CEM and z-FEM were mainly associated with z-cPP and z-pPP variations, respectively. CONCLUSION: Disregard of age and sex, the variations in arterial parameters associated with BP interindividual variations showed differences depending on whether variations were central or peripheral; in SBP, DBP or PP and depending on the arterial segment considered.
INTRODUCTION: The association between arterial parameters and blood pressure (BP) interindividual variations could depend on the arterial segment, BP component (systolic, SBP; diastolic, DBP; pulse pressure, PP) and/or on whether central (cBP) or peripheral (pBP) BP variations are considered. AIM: To assess and compare arterial parameters variations associated with interindividual variations in cBP and pBP. METHODS: Healthy subjects (n = 923; 488 males, 2-84 years) were included. pBP and cBP waves were obtained (Mobil-O-Graph; SphygmoCor). Arterial diameter, intima-media thickness, local elastic modulus (carotid, CEM; brachial, BEM; femoral, FEM) and regional (carotid-radial and carotid-femoral pulse wave velocity; crPWV and cfPWV) arterial stiffness were determined. Associations between BP and arterial parameters interindividual variations were analyzed and compared (correlations; linear regressions; slopes comparisons) considering data transformed into z-scores. RESULTS: Given a variation in z-cSBP or z-pSBP, z-CEM, z-FEM and z-cfPWV (stiffness indexes), were among the parameters with major BP-associated variations. z-crPWV and z-cfPWV, rather than local stiffness indexes were the parameters with major variations associated with z-DBP variations. z-cPP or z-pPP were associated with z-CEM and z-FEM variations, but not with brachial or regional stiffness variations. Most of the arterial parameters-BP slopes did not show significant differences when considering a variation in z-cSBP and z-pSBP. z-CEM and z-FEM were mainly associated with z-cPP and z-pPP variations, respectively. CONCLUSION: Disregard of age and sex, the variations in arterial parameters associated with BP interindividual variations showed differences depending on whether variations were central or peripheral; in SBP, DBP or PP and depending on the arterial segment considered.
Authors: Anastasios Kollias; Styliani Lagou; Maria Elena Zeniodi; Nadia Boubouchairopoulou; George S Stergiou Journal: Hypertension Date: 2015-11-23 Impact factor: 10.190
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Authors: S Curcio; V García-Espinosa; J M Castro; G Peluso; M Marotta; M Arana; P Chiesa; G Giachetto; D Bia; Yanina Zócalo Journal: Pediatr Cardiol Date: 2017-03-13 Impact factor: 1.655
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Authors: S Curcio; V García-Espinosa; M Arana; I Farro; P Chiesa; G Giachetto; Y Zócalo; D Bia Journal: Int J Hypertens Date: 2016-02-18 Impact factor: 2.420
Authors: Victoria Garcia-Espinosa; Daniel Bia; Juan Castro; Agustina Zinoveev; Mariana Marin; Gustavo Giachetto; Pedro Chiesa; Yanina Zócalo Journal: High Blood Press Cardiovasc Prev Date: 2018-07-02
Authors: Juan M Castro; Victoria García-Espinosa; Agustina Zinoveev; Mariana Marin; Cecilia Severi; Pedro Chiesa; Daniel Bia; Yanina Zócalo Journal: J Cardiovasc Dev Dis Date: 2019-09-06