| Literature DB >> 28946372 |
Marine Lambert1, Chanthadary Inthavong1, Frédéric Hommet1, Jean-Charles Leblanc2, Marion Hulin2, Thierry Guérin3.
Abstract
This study describes an optimisation and validation process using liquid chromatography coupled with tandem mass spectrometry to quantify acrylamide in foods mainly consumed by infants and toddlers. A limit of quantification of 5µg.kg-1 for both solid and liquid samples was achieved, except for unprepared infant cereals (LOQ of 18µg.kg-1). The method was then applied to 141 food samples from the first French total diet study on infants and toddlers. Acrylamide was detected in most samples at mean LB/UB concentrations ranging from 0.14 to 102µg.kg-1. The "Follow-on formula" and "Infant formula" products contained the lowest average content (LB/UB of 0.14/2.2µg.kg-1 and 0.60/2.9µg.kg-1 respectively) and the "Sweet and savoury biscuits and bars" (102µg.kg-1; n=1 represented by a plain dry biscuit) contained the highest.Entities:
Keywords: Acrylamide; Acrylamide (PubChem CID: 6579); Foods; Infants and toddlers; LC-MS/MS; Method validation; Total diet study
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Year: 2017 PMID: 28946372 DOI: 10.1016/j.foodchem.2017.08.035
Source DB: PubMed Journal: Food Chem ISSN: 0308-8146 Impact factor: 7.514