Literature DB >> 2894551

Effect of deoxyfructoserotonin (DFS) on lepromatous leprosy.

N H Antia1, E J Ambrose, M W Upleker, P R Mahadevan, L Mester.   

Abstract

To examine the anti-leprosy effect of deoxyfructoserotonin the drug was given in a dose of 10 mg/kg for 6 months to 6 patients with active lepromatous leprosy, in accordance with the WHO-THELEP protocol. Clinical and histological assessment and mouse foot-pad studies suggest that the drug has some anti-leprosy effect.

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Year:  1988        PMID： 2894551     DOI： 10.1016/s0140-6736(88)91417-1

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  3 in total

1.  Effects of a derivative of serotonin (deoxyfructoserotonin) and other antileprosy drugs on attachment and uptake of Mycobacterium leprae by Schwann cells in vitro.

Authors:  A Choudhury; N F Mistry; N H Antia
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191

2.  Metabolism and pharmacokinetics of [14C]-deoxyfructosylserotonin creatinine sulfate administered orally and intravenously to rats and mice.

Authors:  J E Germond; E Gremaud; U Richli; R Badoud; J M Aeschlimann; M J Arnaud
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1993 Apr-Jun       Impact factor: 2.441

Review 3.  Honey--a remedy rediscovered.

Authors:  A Zumla; A Lulat
Journal:  J R Soc Med       Date:  1989-07       Impact factor: 18.000
  3 in total

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