Literature DB >> 28945417

Characterizing the Conformationome: Toward a Structural Understanding of the Proteome.

David E Clemmer1, David H Russell2, Evan R Williams3.   

Abstract

While non-native protein conformations such as folding intermediates are rarely observed in solution such species are often stabilized as gaseous ions during electrospray ionization for mass spectrometry. This opens the possibility of large scale efforts to capture information about many non-native structures such as folding intermediates or malformed conformations having deleterious effects: studies of the conformationome.

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Year:  2017        PMID: 28945417     DOI: 10.1021/acs.accounts.6b00548

Source DB:  PubMed          Journal:  Acc Chem Res        ISSN: 0001-4842            Impact factor:   22.384


  16 in total

1.  Characterizing Thermal Transitions of IgG with Mass Spectrometry.

Authors:  Christopher J Brown; Daniel W Woodall; Tarick J El-Baba; David E Clemmer
Journal:  J Am Soc Mass Spectrom       Date:  2019-07-30       Impact factor: 3.109

2.  First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes.

Authors:  Jacob W McCabe; Christopher S Mallis; Klaudia I Kocurek; Michael L Poltash; Mehdi Shirzadeh; Michael J Hebert; Liqi Fan; Thomas E Walker; Xueyun Zheng; Ting Jiang; Shiyu Dong; Cheng-Wei Lin; Arthur Laganowsky; David H Russell
Journal:  Anal Chem       Date:  2020-07-28       Impact factor: 6.986

3.  Integrating ion mobility and imaging mass spectrometry for comprehensive analysis of biological tissues: A brief review and perspective.

Authors:  Emilio S Rivera; Katerina V Djambazova; Elizabeth K Neumann; Richard M Caprioli; Jeffrey M Spraggins
Journal:  J Mass Spectrom       Date:  2020-09-21       Impact factor: 1.982

4.  Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements.

Authors:  Shannon A Raab; Tarick J El-Baba; Daniel W Woodall; Wen Liu; Yang Liu; Zane Baird; David A Hales; Arthur Laganowsky; David H Russell; David E Clemmer
Journal:  J Am Chem Soc       Date:  2020-09-29       Impact factor: 15.419

5.  Combining Structural Probes in the Gas Phase - Ion Mobility-Resolved Action-FRET.

Authors:  Steven Daly; Luke MacAleese; Philippe Dugourd; Fabien Chirot
Journal:  J Am Soc Mass Spectrom       Date:  2017-10-16       Impact factor: 3.109

6.  Conformational investigation of the structure-activity relationship of GdFFD and its analogues on an achatin-like neuropeptide receptor of Aplysia californica involved in the feeding circuit.

Authors:  Thanh D Do; James W Checco; Michael Tro; Joan-Emma Shea; Michael T Bowers; Jonathan V Sweedler
Journal:  Phys Chem Chem Phys       Date:  2018-08-29       Impact factor: 3.676

7.  Native IM-Orbitrap MS: Resolving What Was Hidden.

Authors:  Michael L Poltash; Jacob W McCabe; Mehdi Shirzadeh; Arthur Laganowsky; David H Russell
Journal:  Trends Analyt Chem       Date:  2019-05-31       Impact factor: 12.296

8.  Optimizing Native Ion Mobility Q-TOF in Helium and Nitrogen for Very Fragile Noncovalent Structures.

Authors:  Valérie Gabelica; Sandrine Livet; Frédéric Rosu
Journal:  J Am Soc Mass Spectrom       Date:  2018-07-25       Impact factor: 3.109

Review 9.  THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY.

Authors:  Jacob W McCabe; Michael J Hebert; Mehdi Shirzadeh; Christopher S Mallis; Joanna K Denton; Thomas E Walker; David H Russell
Journal:  Mass Spectrom Rev       Date:  2020-07-01       Impact factor: 10.946

10.  Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding.

Authors:  Jacob W McCabe; Mehdi Shirzadeh; Thomas E Walker; Cheng-Wei Lin; Benjamin J Jones; Vicki H Wysocki; David P Barondeau; David E Clemmer; Arthur Laganowsky; David H Russell
Journal:  Anal Chem       Date:  2021-04-27       Impact factor: 6.986

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