| Literature DB >> 28945417 |
David E Clemmer1, David H Russell2, Evan R Williams3.
Abstract
While non-native protein conformations such as folding intermediates are rarely observed in solution such species are often stabilized as gaseous ions during electrospray ionization for mass spectrometry. This opens the possibility of large scale efforts to capture information about many non-native structures such as folding intermediates or malformed conformations having deleterious effects: studies of the conformationome.Mesh:
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Year: 2017 PMID: 28945417 DOI: 10.1021/acs.accounts.6b00548
Source DB: PubMed Journal: Acc Chem Res ISSN: 0001-4842 Impact factor: 22.384