Literature DB >> 28944272

The effect of environmental temperature on exercise-dependent release of brain-derived neurotrophic factor.

Christopher W Collins1, Robert J Shute1, Matthew W S Heesch1, Dustin R Slivka1.   

Abstract

Brain-derived neurotrophic factor (BDNF) is a biomarker of cognitive function that is released into the blood stream following exercise, and cognitive function is impaired by environmental temperatures that are hot and cold. Purpose: To evaluate the exercise-dependent release of BDNF in different environmental temperatures.
Methods: Recreationally trained males each completed three trials consisting of cycling for 1 h at 60% Wmax at three different temperatures: 33°C (hot), 7°C (cold), and 20°C (moderate room temperature). Blood was taken from the antecubital vein pre-exercise, immediately post-exercise, and 3 h post-exercise. Respiratory gases were collected periodically throughout exercise and recovery.
Results: BDNF was elevated immediately following an exercise bout (1711 ± 766 pg·ml-1) regardless of temperature from pre-exercise (1257 ± 653 pg·ml-1, p = 0.001) and returned to basal levels following 3 h of recovery (1289 ± 650 pg·ml-1, p = 0.786). There was no effect (p > 0.05) of temperature on BDNF following the exercise bout. Plasma glucose was elevated in hot (6.2 ± 0.9 mmol) over cold (5.3 ± 0.6 mmol, p = 0.035) and moderate room temperature (5.2 ± 0.5, p = 0.008). VO2 was elevated during exercise in hot (3.01 ± 0.45 L·min-1) over cold (2.67 ± 0.35 L·min-1, p = 0.005) and moderate room temperature (2.80 ± 0.38 L·min-1, p = 0.001). There was no relationship between BDNF and plasma glucose (p > 0.05) or VO2 across any time point or temperature (p > 0.05).
Conclusion: With aerobic exercise, BDNF is elevated; however, the release of BDNF is not impacted by different environmental temperatures during exercise.

Entities:  

Keywords:  BDNF; ELISA; cycling; exercise; glucose; heat

Year:  2017        PMID: 28944272      PMCID: PMC5605157          DOI: 10.1080/23328940.2017.1328304

Source DB:  PubMed          Journal:  Temperature (Austin)        ISSN: 2332-8940


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