Literature DB >> 28944146

Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario.

Ayan Basu1, Arvind Kumar1, Smita Manchanda2, Naveet Wig1.   

Abstract

Lymphatic filariasis is caused by nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaraemia, acute lymphatic filariasis (lymphangitis and lymphoedema), chronic lymphoedema, elephantiasis, hydrocele, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve, etc. We here present a case of huge splenomegaly caused by lymphatic filariasis which is a rare presentation and only few cases had been reported in the world literature so far. After treatment of filariasis spleen size was reduced dramatically and patient is doing well even after 6 months of follow up after therapy.

Entities:  

Keywords:  Filariasis; lymphatic; splenomegaly

Year:  2017        PMID: 28944146      PMCID: PMC5608934          DOI: 10.5582/irdr.2017.01041

Source DB:  PubMed          Journal:  Intractable Rare Dis Res        ISSN: 2186-3644


  11 in total

1.  489 Global programme to eliminate lymphatic filariasis: progress report, 2014.

Authors: 
Journal:  Wkly Epidemiol Rec       Date:  2015-09-18

2.  Microfilaria of Wuchereria bancrofti in bone marrow smear.

Authors:  S Pradhan; V L Lahiri; B R Elhence; K N Singh
Journal:  Am J Trop Med Hyg       Date:  1976-01       Impact factor: 2.345

3.  Microfilariae in bone marrow aspiration smears.

Authors:  U Shenoi; R R Pai; U Pai; G K Nandi; P Adhikari
Journal:  Acta Cytol       Date:  1998 May-Jun       Impact factor: 2.319

4.  Microfilariae in cytologic smears: a report of six cases.

Authors:  R Varghese; C V Raghuveer; M R Pai; R Bansal
Journal:  Acta Cytol       Date:  1996 Mar-Apr       Impact factor: 2.319

5.  Microfilariae of Wucheria bancrofti in bone marrow.

Authors:  Uzma Zafar; Khaliqur Rahman; Rana K Sherwani; Mohammad Shahid
Journal:  Indian J Hematol Blood Transfus       Date:  2009-04-06       Impact factor: 0.900

6.  Blastic Phase of CML with Microfilaria: A Rare Case Report.

Authors:  Suniti Pahwa; Annapurna Saksena; Ashu Singh; M K Daga; Tejinder Singh
Journal:  J Clin Diagn Res       Date:  2015-01-01

7.  Acute lymphoblastic leukaemia with microfilaria: a rare coincidence in bone marrow aspirate.

Authors:  Ashok Kumar; Rakesh Kumar
Journal:  Indian J Hematol Blood Transfus       Date:  2011-05-07       Impact factor: 0.900

8.  Microfilariae with acute myeloid leukemia: a common parasite with uncommon association.

Authors:  Khaliqur Rahman; Seena George; Manjula Sardana; Anurag Mehta
Journal:  Indian J Hematol Blood Transfus       Date:  2012-04-18       Impact factor: 0.900

9.  Aplastic anaemia following varicella infection with coexistent microfilaremia of Wuchereria bancrofti--a case report.

Authors:  Manikkapurath Hemachandran; Neelam Varma; Subhash Varma
Journal:  Indian J Pathol Microbiol       Date:  2003-10       Impact factor: 0.740

10.  Diethylcarbamazine in the control of bancroftian filariasis in the Ok Tedi area of Papua New Guinea: phase 2--annual single-dose treatment.

Authors:  G J Schuurkamp; R K Kereu; P K Bulungol; A Kawereng; P E Spicer
Journal:  P N G Med J       Date:  1994-06
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