| Literature DB >> 28942684 |
Ali El-Gamal1,2, Shaza Al-Massarani1, Ghada Fawzy1,3, Hanan Ati1, Adnan Al-Rehaily1, Omer Basudan1, Maged Abdel-Kader4, Nurhayat Tabanca5, James Becnel6.
Abstract
A new acylatediridoid glycoside, 6-O-α-L-(2″-acetyl-4″-O-trans-isoferuloyl) rhamnopyranosyl catalpol (9) together with 18 known compounds belonging to the iridoids, flavonoids, triterpene saponin glycosides and phenylethanoids (1-8, 10-18) were isolated from the aerial parts and the flowers of Buddleja polystachya. Their structures were elucidated on the basis of spectroscopic evidence and comparison with that reported in the literature. Promising adulticidal activity was shown for all extracts when tested for adulticidal and larvicidal activities against Ae. aegypti mosquitoes. Therefore, isolated compounds (1-10, 12-14 and 19) were bioassayed for their adulticidal activity. Compound 1 (phytol) was highly active with an LD50 value of 1.27 ± 0.08 μg/mosquito against adult female Ae. aegypti.Entities:
Keywords: Buddleja polystachya; acylated iridoid glycosides; adulticidal; larvicidal
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Year: 2017 PMID： 28942684 DOI： 10.1080/14786419.2017.1378213
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861