Literature DB >> 28941494

Current Understanding of the Genetic Causes of Keloid Formation.

Donald A Glass1.   

Abstract

Keloids are an exuberant response to cutaneous wound healing. Several lines of evidence suggest that keloid scarring is influenced by genetic factors. This review will discuss our current understanding of genetic influences on keloidal scarring via familial inheritance patterns; ethnic differences in prevalence; syndromes with keloid occurrence; linkage analysis, genome-wide association studies, and admixture mapping studies; transforming growth factor beta and p53 variant studies; and human leukocyte antigen polymorphisms.
Copyright © 2016 The Author. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28941494     DOI: 10.1016/j.jisp.2016.10.024

Source DB:  PubMed          Journal:  J Investig Dermatol Symp Proc        ISSN: 1087-0024


  24 in total

Review 1.  A Retrospective Registry Study Evaluating the Long-Term Efficacy and Safety of Superficial Radiation Therapy Following Excision of Keloid Scars.

Authors:  Brian Berman; Mark S Nestor; Michael H Gold; David J Goldberg; Eduardo T Weiss; Isabelle Raymond
Journal:  J Clin Aesthet Dermatol       Date:  2020-10-01

2.  A Retrospective Cohort Study and Clinical Classification System of Acne Keloidalis Nuchae.

Authors:  Sanusi Umar; Delphine J Lee; Jenna J Lullo
Journal:  J Clin Aesthet Dermatol       Date:  2021-04-01

3.  STAT3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses.

Authors:  Yun-Shain Lee; Ya-Chen Liang; Ping Wu; David A Kulber; Kylie Tanabe; Cheng-Ming Chuong; Randall Widelitz; Tai-Lan Tuan
Journal:  Exp Dermatol       Date:  2019-04       Impact factor: 3.960

4.  Role of hTERT rs2736100 in pathological scarring.

Authors:  Roxana Flavia Ilieș; Salomea-Ruth Halmagyi; Andreea Cătană; Casian Simon Aioanei; Istvan Lukacs; Reka-Eniko Tokes; Ioana Cristina Rotar; Ioan Victor Pop
Journal:  Exp Ther Med       Date:  2022-02-04       Impact factor: 2.447

5.  IL-4 and CCR7 play an important role in the development of keloids in patients with a family history.

Authors:  Mengjie Shan; Hao Liu; Yan Hao; Tian Meng; Cheng Feng; Kexin Song; Youbin Wang
Journal:  Am J Transl Res       Date:  2022-05-15       Impact factor: 3.940

6.  A prospective, randomized assessment of a novel, local antibiotic releasing platform for the prevention of superficial and deep surgical site infections.

Authors:  O Zmora; Y Stark; O Belotserkovsky; M Reichert; G A Kozloski; N Wasserberg; H Tulchinsky; L Segev; A J Senagore; N Emanuel
Journal:  Tech Coloproctol       Date:  2022-09-01       Impact factor: 3.699

7.  Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids.

Authors:  Jiaqi Liu; Huayu Zhu; Hongtao Wang; Jun Li; Fu Han; Yang Liu; Wanfu Zhang; Ting He; Na Li; Zhao Zheng; Dahai Hu
Journal:  J Mol Histol       Date:  2018-02-17       Impact factor: 2.611

8.  Efficacy and safety of laser combination therapy and laser alone therapy for keloid: a systematic review and meta-analysis.

Authors:  Jiahui Chen; Aiyue Chen; Jianhao Zhang; Feipeng Wang; Qiongfang Fang; Ziwei He; Xi Chen; Wancheng Ma; Fulan Hu
Journal:  Lasers Med Sci       Date:  2021-07-20       Impact factor: 3.161

Review 9.  Current Advances in Hypertrophic Scar and Keloid Management.

Authors:  Natasha Barone; Tyler Safran; Joshua Vorstenbosch; Peter G Davison; Sabrina Cugno; Amanda M Murphy
Journal:  Semin Plast Surg       Date:  2021-07-15       Impact factor: 2.195

10.  The 10-Point Plan 2021: Updated Concepts for Improved Procedural Safety During Facial Filler Treatments.

Authors:  Izolda Heydenrych; Koenraad De Boulle; Krishan Mohan Kapoor; Dario Bertossi
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-07-06
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