Literature DB >> 28940112

Iron in kidney and heart failure: from theory to practice.

Aslihan Yerlikaya1, Mustafa C Bulbul1, Baris Afsar2, Tuncay Dagel3, Gamze Aslan4, Luminita Voroneanu5, Dimitire Siriopol5, Adrian Covic5, Mehmet Kanbay6.   

Abstract

There is evidence that serum iron levels, regardless of the presence of anemia, directly impact outcomes in congestive heart failure (CHF) including quality of life, hospitalization rate and overall survival. Despite modern medical treatments, the prognosis of CHF remains grim. Ironically, simple iron replenishment may serve as a powerful tool in the armamentarium. This review will start from fundamental concepts of iron in oxygen delivery and analyze evidence-based outcomes in CHF iron-directed therapeutic trials. Imaging rationale that dovetails with this pathophysiology will also be detailed in a clinician-directed fashion.

Entities:  

Keywords:  Heart failure; Iron deficiency; Iron replacement; Kidney disease

Mesh：

Substances：

Year:  2017        PMID： 28940112     DOI： 10.1007/s11255-017-1708-6

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  65 in total

Review 1.  The influence of iron deficiency on the functioning of skeletal muscles: experimental evidence and clinical implications.

Authors:  Magdalena Stugiewicz; Michał Tkaczyszyn; Monika Kasztura; Waldemar Banasiak; Piotr Ponikowski; Ewa A Jankowska
Journal:  Eur J Heart Fail       Date:  2016-01-21       Impact factor: 15.534

2.  Intravenous iron alone for the treatment of anemia in patients with chronic heart failure.

Authors:  Aidan P Bolger; Frederick R Bartlett; Helen S Penston; Justin O'Leary; Noel Pollock; Raffi Kaprielian; Callum M Chapman
Journal:  J Am Coll Cardiol       Date:  2006-08-28       Impact factor: 24.094

3.  Changes in Echocardiographic Parameters in Iron Deficiency Patients with Heart Failure and Chronic Kidney Disease Treated with Intravenous Iron.

Authors:  Jorge E Toblli; Federico Di Gennaro; Carlos Rivas
Journal:  Heart Lung Circ       Date:  2015-01-21       Impact factor: 2.975

4.  Heart failure not enough pump iron?

Authors:  John McMurray; Piotr Ponikowski
Journal:  J Am Coll Cardiol       Date:  2011-07-26       Impact factor: 24.094

5.  Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure.

Authors:  T Tsutamoto; T Hisanaga; A Wada; K Maeda; M Ohnishi; D Fukai; N Mabuchi; M Sawaki; M Kinoshita
Journal:  J Am Coll Cardiol       Date:  1998-02       Impact factor: 24.094

Review 6.  Iron deficiency in patients with heart failure.

Authors:  Sarah Fitzsimons; Robert Neil Doughty
Journal:  Eur Heart J Cardiovasc Pharmacother       Date:  2015-01

7.  Endotoxin and immune activation in chronic heart failure: a prospective cohort study.

Authors:  J Niebauer; H D Volk; M Kemp; M Dominguez; R R Schumann; M Rauchhaus; P A Poole-Wilson; A J Coats; S D Anker
Journal:  Lancet       Date:  1999-05-29       Impact factor: 79.321

Review 8.  Anemia in Cardio-Renal Syndrome: clinical impact and pathophysiologic mechanisms.

Authors:  Alberto Palazzuoli; Giovanni Antonelli; Ranuccio Nuti
Journal:  Heart Fail Rev       Date:  2011-11       Impact factor: 4.214

9.  Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia.

Authors:  Jalal K Ghali; Inder S Anand; William T Abraham; Gregg C Fonarow; Barry Greenberg; Henry Krum; Barry M Massie; Scott M Wasserman; Marie-Louise Trotman; Yan Sun; Beat Knusel; Paul Armstrong
Journal:  Circulation       Date:  2008-01-14       Impact factor: 29.690

10.  Correction of iron deficiency in the cardiorenal syndrome.

Authors:  Donald S Silverberg; Dov Wexler; Adrian Iaina; Doron Schwartz
Journal:  Int J Nephrol       Date:  2011-04-19
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  2 in total

1.  A prospective cohort examination of haematological parameters in relation to cancer death and incidence: the Busselton Health Study.

Authors:  Niwansa Adris; Anita Chai Geik Chua; Matthew William Knuiman; Mark Laurence Divitini; Debbie Trinder; John Kevin Olynyk
Journal:  BMC Cancer       Date:  2018-09-03       Impact factor: 4.430

2.  A journey from microenvironment to macroenvironment: the role of metaflammation and epigenetic changes in cardiorenal disease.

Authors:  Mehmet Kanbay; Aslihan Yerlikaya; Alan A Sag; Alberto Ortiz; Masanari Kuwabara; Adrian Covic; Andrzej Wiecek; Peter Stenvinkel; Baris Afsar
Journal:  Clin Kidney J       Date:  2019-09-18
  2 in total

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