Literature DB >> 28939983

[Drug therapy for older people : Choosing wisely].

Martin Wehling1.   

Abstract

Elderly people are the most rapidly growing sector of our society. Due to their multimorbidity they are exposed to a multitude of medications, which are accompanied by chances and risks. The problem of inappropriate medication in the elderly is exacerbated by the fact that only a holistic view can help these patients and that this is predominantly the responsibility of the general practitioner. The closely measured paid contact time is often insufficient to optimize complex medications. Clinically successfully tested aids in the form of lists give reason for hope: in particular, the positive/negative assessment of limitations of the elderly with respect to drugs by the STOPP/START criteria and the FORTA classification are clinically successful aids. Purely negative lists, such as the Beers or PRISCUS lists, have been disappointing in clinical application because they do not consider the needs, prognostic and particularly symptomatic importance and weighting of the diagnosis of patients. Further implementation of these aids to decision making should help to improve the problem of care of elderly patients in the field of drug treatment, even in IT systems.

Entities:  

Keywords:  Benefit-risk assessment; Drug-related side effects and adverse reactions; Medication therapy management; Multimorbidity; Polypharmacy

Mesh:

Year:  2017        PMID: 28939983     DOI: 10.1007/s00391-017-1312-5

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  12 in total

1.  [Drug therapy in the elderly: too much or too little, what to do? A new assessment system: fit for the aged (FORTA].

Authors:  M Wehling
Journal:  Dtsch Med Wochenschr       Date:  2008-10-22       Impact factor: 0.628

2.  Multimorbidity in general practice: prevalence, incidence, and determinants of co-occurring chronic and recurrent diseases.

Authors:  M van den Akker; F Buntinx; J F Metsemakers; S Roos; J A Knottnerus
Journal:  J Clin Epidemiol       Date:  1998-05       Impact factor: 6.437

3.  Guideline-driven polypharmacy in elderly, multimorbid patients is basically flawed: there are almost no guidelines for these patients.

Authors:  Martin Wehling
Journal:  J Am Geriatr Soc       Date:  2011-02       Impact factor: 5.562

Review 4.  Explicit criteria for determining potentially inappropriate medication use by the elderly. An update.

Authors:  M H Beers
Journal:  Arch Intern Med       Date:  1997-07-28

5.  Older People, a Plethora of Drugs, and Drug List Approaches: Useful, Efficacious, or a Waste of Time?

Authors:  Martin Wehling
Journal:  J Am Med Dir Assoc       Date:  2016-10-15       Impact factor: 4.669

6.  VALFORTA: a randomised trial to validate the FORTA (Fit fOR The Aged) classification.

Authors:  Martin Wehling; Heinrich Burkhardt; Alexandra Kuhn-Thiel; Farhad Pazan; Christina Throm; Christel Weiss; Helmut Frohnhofen
Journal:  Age Ageing       Date:  2016-01-18       Impact factor: 10.668

7.  Potentially inappropriate medications in the elderly: the PRISCUS list.

Authors:  Stefanie Holt; Sven Schmiedl; Petra A Thürmann
Journal:  Dtsch Arztebl Int       Date:  2010-08-09       Impact factor: 5.594

8.  Prevention of Hospital-Acquired Adverse Drug Reactions in Older People Using Screening Tool of Older Persons' Prescriptions and Screening Tool to Alert to Right Treatment Criteria: A Cluster Randomized Controlled Trial.

Authors:  Marie N O'Connor; David O'Sullivan; Paul F Gallagher; Joseph Eustace; Stephen Byrne; Denis O'Mahony
Journal:  J Am Geriatr Soc       Date:  2016-07-01       Impact factor: 5.562

9.  [Polypharmacy in the elderly - choosing wisely by using the FORTA list].

Authors:  Martin Wehling; Christina Throm
Journal:  Dtsch Med Wochenschr       Date:  2015-09-11       Impact factor: 0.628

Review 10.  STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.

Authors:  Denis O'Mahony; David O'Sullivan; Stephen Byrne; Marie Noelle O'Connor; Cristin Ryan; Paul Gallagher
Journal:  Age Ageing       Date:  2014-10-16       Impact factor: 10.668

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  2 in total

1.  [Cardiovascular pharmacotherapy in the elderly : To avoid overtreatment and undertherapy].

Authors:  J Bauersachs; M Wehling
Journal:  Herz       Date:  2018-05       Impact factor: 1.443

2.  Associations Between Low-Value Medication in Dementia and Healthcare Costs.

Authors:  Moritz Platen; Steffen Flessa; Anika Rädke; Diana Wucherer; Jochen René Thyrian; Annelie Scharf; Wiebke Mohr; Franka Mühlichen; Wolfgang Hoffmann; Bernhard Michalowsky
Journal:  Clin Drug Investig       Date:  2022-04-28       Impact factor: 3.580

  2 in total

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