| Literature DB >> 28939977 |
Yin Xiang Setoh1, Alberto A Amarilla1, Nias Y Peng1, Andrii Slonchak1, Parthiban Periasamy1, Luiz T M Figueiredo2, Victor H Aquino3, Alexander A Khromykh4.
Abstract
Rocio virus (ROCV) is an arbovirus belonging to the genus Flavivirus, family Flaviviridae. We present an updated sequence of ROCV strain SPH 34675 (GenBank: AY632542.4), the only available full genome sequence prior to this study. Using next-generation sequencing of the entire genome, we reveal substantial sequence variation from the prototype sequence, with 30 nucleotide differences amounting to 14 amino acid changes, as well as significant changes to predicted 3'UTR RNA structures. Our results present an updated and corrected sequence of a potential emerging human-virulent flavivirus uniquely indigenous to Brazil (GenBank: MF461639).Entities:
Mesh：
Substances：
Year: 2017 PMID： 28939977 DOI： 10.1007/s00705-017-3561-4
Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574