| Literature DB >> 2893827 |
Y Li1, P Szabo, D N Posnett.
Abstract
New RFLP of the human TCR gamma-chain defined by a single restriction enzyme (PvuII) are described. They define three alleles and allow haplotype assignments within families. They occur at a high frequency within the population studied and are useful for studies on disease associations with the gamma-chain genes. The PvuII sites flank the C gamma 2 gene. A polymorphic site maps to an area 0.5 kb downstream of C gamma 2-exon III. The second RFLP appears to be the result of a 3-kb insertion giving rise to differences in the number of copies of exon II in the C gamma 2 gene.Entities:
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Year: 1988 PMID： 2893827
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422