Literature DB >> 2893733

Successful treatment of recurrent cerebral empyema and brain abscesses with imipenem.

J A Carton1, F Perez, J A Maradona, F J Mendez.   

Abstract

Imipenem was successfully used to treat a case of subdural empyema complicated by multiple cerebral abscesses, in which surgery and therapy with other antibiotics had previously failed. Imipenem concentrations in serum, cerebrospinal fluid and the cerebral abscess were much higher than the MICs for the infecting organisms, qualifying this antibiotic as an effective option in therapy of suppurative intracranial infections.

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Year:  1987        PMID： 2893733     DOI： 10.1007/bf02014252

Source DB:  PubMed          Journal:  Eur J Clin Microbiol        ISSN： 0722-2211            Impact factor:   3.267


  8 in total

1.  The safety profile of imipenem/cilastatin: worldwide clinical experience based on 3470 patients.

Authors:  G B Calandra; C Wang; M Aziz; K R Brown
Journal:  J Antimicrob Chemother       Date:  1986-12       Impact factor: 5.790

2.  Penetration of imipenem and cilastatin into cerebrospinal fluid of patients with bacterial meningitis.

Authors:  J Modai; D Vittecoq; J M Decazes; A Meulemans
Journal:  J Antimicrob Chemother       Date:  1985-12       Impact factor: 5.790

3.  Imipenem: the first thienamycin antibiotic.

Authors:  A M Geddes; W Stille
Journal:  Rev Infect Dis       Date:  1985 Jul-Aug

Review 4.  Efficacy and safety of imipenem/cilastatin: a review of worldwide clinical experience.

Authors:  C Wang; G B Calandra; M A Aziz; K R Brown
Journal:  Rev Infect Dis       Date:  1985 Jul-Aug

5.  Treatment of subdural empyema.

Authors:  G Bannister; B Williams; S Smith
Journal:  J Neurosurg       Date:  1981-07       Impact factor: 5.115

6.  Comparison of cefotaxime, imipenem-cilastatin, ampicillin-gentamicin, and ampicillin-chloramphenicol in the treatment of experimental Escherichia coli bacteremia and meningitis.

Authors:  K S Kim
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

7.  Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin.

Authors:  J Birnbaum; F M Kahan; H Kropp; J S MacDonald
Journal:  Am J Med       Date:  1985-06-07       Impact factor: 4.965

Review 8.  Antibacterial activity of imipenem: the first thienamycin antibiotic.

Authors:  H Kropp; L Gerckens; J G Sundelof; F M Kahan
Journal:  Rev Infect Dis       Date:  1985 Jul-Aug
  8 in total
  1 in total

1.  Imipenem therapy of brain abscesses.

Authors:  V Asensi; J A Carton; J A Maradona; J M Asensi; F Pérez; P Redondo; A López; J M Arribas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1996-08       Impact factor: 3.267
  1 in total

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