Literature DB >> 2893611

Modulation of c-myc by transforming growth factor-beta in human colon carcinoma cells.

K M Mulder1, A E Levine, X Hernandez, M K McKnight, D E Brattain, M G Brattain.   

Abstract

Previous work indicated that transforming growth factor-beta elicits proliferation-inhibitory and differentiation-like effects in the human colon carcinoma cell line MOSER. We report for the first time that the proto-oncogene c-myc is repressed in response to transforming growth factor-beta in a human colon carcinoma cell line. We also describe a subline of these cells which are relatively resistant to the transforming growth factor-beta-induced effects on proliferation in monolayer and in soft agarose, but which retain the ability to specifically bind transforming growth factor-beta. Analysis of molecular and cellular alterations in this subline may aid in elucidating the mechanism of action of transforming growth factor-beta.

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Year:  1988        PMID： 2893611     DOI： 10.1016/0006-291x(88)90449-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  14 in total

1.  Role of Radiation-induced TGF-beta Signaling in Cancer Therapy.

Authors:  Horatiu C Dancea; Mohammed M Shareef; Mansoor M Ahmed
Journal:  Mol Cell Pharmacol       Date:  2009

2.  A new cell line from human undifferentiated carcinoma of the ovary: establishment and characterization.

Authors:  J W Kim; C G Lee; M S Lyu; H K Kim; J G Rha; D H Kim; S J Kim; S E Namkoong
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

Review 3.  Tumors as organs: biologically augmenting radiation therapy by inhibiting transforming growth factor β activity in carcinomas.

Authors:  Shisuo Du; Mary Helen Barcellos-Hoff
Journal:  Semin Radiat Oncol       Date:  2013-10       Impact factor: 5.934

4.  TGF-beta gene expression depends on tissue architecture.

Authors:  D Theodorescu; C Sheehan; R S Kerbel
Journal:  In Vitro Cell Dev Biol       Date:  1993-02

5.  Regulation of transforming growth factor expression in rat intestinal epithelial cell lines.

Authors:  S Suemori; C Ciacci; D K Podolsky
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

6.  Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta.

Authors:  S B Jakowlew; J E Mead; D Danielpour; J Wu; A B Roberts; N Fausto
Journal:  Cell Regul       Date:  1991-07

Review 7.  The tale of transforming growth factor-beta (TGFbeta) signaling: a soigné enigma.

Authors:  Arindam Chaudhury; Philip H Howe
Journal:  IUBMB Life       Date:  2009-10       Impact factor: 3.885

8.  Characterization of the DiFi rectal carcinoma cell line derived from a familial adenomatous polyposis patient.

Authors:  M Olive; S Untawale; R J Coffey; M J Siciliano; D M Wildrick; H Fritsche; S Pathak; L M Cherry; M Blick; P Lointier
Journal:  In Vitro Cell Dev Biol       Date:  1993-03

9.  Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acids.

Authors:  M J Newman
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

10.  Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells.

Authors:  Shu Lin; Junhua Yang; Abdel G Elkahloun; Abhik Bandyopadhyay; Long Wang; John E Cornell; I-Tien Yeh; Joseph Agyin; Gail Tomlinson; Lu-Zhe Sun
Journal:  Mol Biol Cell       Date:  2012-02-22       Impact factor: 4.138
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