| Literature DB >> 2893487 |
S Hirose1, S Kotani, Y Uemura, M Fujishita, H Taguchi, Y Ohtsuki, I Miyoshi.
Abstract
The mode of vertical transmission of human T-cell leukemia virus type I (HTLV-I) was investigated by foster-nursing in rabbits. Two of five rabbits born to noninfected mothers and fostered by virus-infected females seroconverted for HTLV-I after 7 weeks, whereas all seven rabbits born to virus-infected mothers and fostered by noninfected females remained seronegative for the observation period of 6 months. Culture of peripheral blood lymphocytes gave rise to an HTLV-I-carrying T-cell line from each of the two seroconverted rabbits. These findings suggest that HTLV-I is transmitted through milk from mother to offspring.Entities:
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Year: 1988 PMID: 2893487 DOI: 10.1016/0042-6822(88)90492-8
Source DB: PubMed Journal: Virology ISSN: 0042-6822 Impact factor: 3.616