Literature DB >> 28933276

Cyclophosphamide and/or Anthracyclines Induced Epiphora in Breast Cancer Patients: A Rare Side-effect.

Ruchika Kalra1, Bhavesh Chavada1, Nishant R Madhani2, Bhargav Purohit1, C B Tripathi1.   

Abstract

BACKGROUND: Two female breast cancer patients developed epiphora after administration of cyclophosphamide and/or anthracyclines based 2-day chemotherapy regimen. An ophthalmologist was consulted and no apparent cause was found. CASE DESCRIPTION: Patients were managed by ciprofloxacin eye drops. Chemotherapy induced ocular complications are not uncommon, but under reported. Although epiphora is a mild reaction, if severe however, it can interfere with daily activities. Patients having chemotherapy induced ocular toxicity should go for ophthalmic examination to pick up ocular adverse effects of anticancer drugs and treat them at an early stage. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Cyclophosphamide; anthracyclines; chemotherapy; epiphora; ocular adverse effects.; ophthalmic examination

Mesh:

Substances:

Year:  2018        PMID: 28933276     DOI: 10.2174/1574886312666170919175614

Source DB:  PubMed          Journal:  Curr Drug Saf        ISSN: 1574-8863


  2 in total

1.  Overexpression of CLEC3A promotes tumor progression and poor prognosis in breast invasive ductal cancer.

Authors:  Jun Ni; Yun Peng; Fu-Lan Yang; Xun Xi; Xing-Wei Huang; Chun He
Journal:  Onco Targets Ther       Date:  2018-06-04       Impact factor: 4.147

2.  Prevalence of symptomatic dry eye in breast cancer patients undergoing systemic adjuvant treatment: A cross-sectional study.

Authors:  Jinfei Ma; Emmanuel Eric Pazo; Zihao Zou; Feng Jin
Journal:  Breast       Date:  2020-08-05       Impact factor: 4.380

  2 in total

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